Variables | CAD (+) | CAD (−) | P value |
---|---|---|---|
(n = 144) | (n = 61) | ||
Male, n (%) | 108 (75.0) | 37 (60.7) | 0.039 |
Age, years | 64.8 ± 10.3 | 65.3 ± 9.1 | 0.728 |
Body mass index, Kg/m2 | 25.5 ± 3.4 | 24.9 ± 3.1 | 0.262 |
Smoking, n (%) | 50 (34.7) | 11 (18.0) | 0.017 |
Hypertension (%) | 110 (76.4) | 37 (60.7) | 0.022 |
Systolic blood pressure, mmHg | 140 ± 19 | 139 ± 20 | 0.572 |
Diastolic blood pressure,mmHg | 81 ± 12 | 81 ± 11 | 0.603 |
Dyslipidemia history, n (%) | 57 (39.6) | 23 (37.7) | 0.801 |
Triglycerides, mmol/L | 1.82 ± 1.09 | 1.75 ± 0.96 | 0.671 |
Total cholesterol, mmol/L | 4.3 ± 1.2 | 4.4 ± 1.0 | 0.753 |
HDL cholesterol, mmol/L | 1.01 ± 0.24 | 1.13 ± 0.22 | 0.001 |
LDL cholesterol, mmol/L | 2.63 ± 0.93 | 2.56 ± 0.76 | 0.616 |
Lipoprotein (a), g/L | 0.27 ± 0.25 | 0.28 ± 0.26 | 0.666 |
Apoprotein A, g/L | 1.20 ± 0.19 | 1.23 ± 0.20 | 0.310 |
Apoprotein B, g/L | 0.91 ± 0.26 | 0.88 ± 0.20 | 0.460 |
Serum creatinine, μmol/L | 81 ± 17 | 75 ± 14 | 0.011 |
eGFR, mL/min/1.73 m2 | 92.3 ± 24.4 | 96.8 ± 23.6 | 0.228 |
Uric acid, μmol/L | 342 ± 89 | 325 ± 83 | 0.199 |
Fasting blood glucose, mmol/L | 6.79 ± 2.00 | 6.02 ± 1.33 | 0.001 |
HbA1c, % | 7.81 ± 1.07 | 6.89 ± 0.75 | <0.001 |
hsCRP, mg/L | 6.20 ± 3.24 | 5.21 ± 2.42 | 0.040 |
Extent index | 0.48 ± 0.13 | 0.27 ± 0.08 | <0.001 |
Cumulative coronary stenosis score | 2.17 ± 0.71 | 0.92 ± 0.42 | <0.001 |
Relative intensity of apoA-I glycation, % | 8.27 ± 2.09 | 5.69 ± 1.42 | <0.001 |
Activities of paraoxonase, U/mL | |||
 Serum PON1 activity | 78.46 ± 16.94 | 86.01 ± 17.36 | 0.004 |
 HDL-associated PON1 activity | 41.43 ± 14.64 | 92.19 ± 33.42 | <0.001 |
 Serum PON3 activity | 32.15 ± 5.33 | 39.2 ± 6.62 | <0.001 |
 HDL-associated PON3 activity | 26.06 ± 12.66 | 64.58 ± 22.44 | <0.001 |
Medical treatments, n (%) | |||
 Insulins | 51 (35.4) | 11 (18.0) | 0.013 |
 Metformin | 70 (48.6) | 31 (50.8) | 0.772 |
 Sulphonylurea | 41 (28.5) | 25 (41.0) | 0.080 |
 α-Glucosidase | 40 (27.8) | 18 (29.5) | 0.801 |
 Statin | 107 (74.3) | 43 (70.5) | 0.573 |
 ACE inhibitor/ARB | 88 (61.1) | 37 (60.7) | 0.951 |
 β-blocker | 82 (56.9) | 34 (55.7) | 0.873 |
 Calcium channel blocker | 73 (50.7) | 39 (63.9) | 0.082 |
 Antiplatelet | 107 (74.3) | 36 (59.0) | 0.029 |