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Table 4 Odds ratio of NWO for increased subclinical atherosclerosis

From: Normal-weight obesity is associated with increased risk of subclinical atherosclerosis

 

Odds ratio (95 % CI)

P-value

 

NWL

NWO

 

n = 1795

n = 283

PWV (highest tertile)

   

 Model 1

1.000 (Reference)

2.008 (1.557 - 2.591)

<0.001

 Model 2

1.394 (1.043 - 1.862)

0.025

 Model 3

1.254 (0.927 -1.694)

0.142

Any plaque

   

 Model 1

1.000 (Reference)

1.494 (1.160 - 1.924)

0.002

 Model 2

1.271 (0.954 - 1.693)

0.101

Soft plaque

   

 Model 1

1.000 (Reference)

1.615 (1.182 - 2.207)

0.003

 Model 2

1.586 (1.146 - 2.194)

0.005

 Model 3

1.515 (1.084 - 2.116)

0.015

 Model 4

1.539 (1.100 - 2.154)

0.012

 Model 5

1.555 (1.110 - 2.177)

0.010

 Model 6

1.460 (1.027 - 2.074)

0.035

  1. For PWV, the odds ratio for being in the highest tertile of PMV was analyzed. For any coronary plaque or soft plaque, the odds ratio for having these characteristics was analyzed for NWO subjects as compared with the NWL subjects
  2. Model 1 : before adjustment
  3. Model 2 : adjusted for age and sex
  4. Model 3 : adjusted for age, sex, systolic BP, fasting glucose, HDL, CRP
  5. Model 4: adjusted for age, sex, systolic BP, fasting glucose, HDL, CRP, anti-hypertension medication, antidiabetic medication, lipid lowering agent, antiplatelet agent
  6. Model 5: adjusted for age, sex, systolic BP, fasting glucose, HDL, CRP, anti-hypertension medication, antidiabetic medication, lipid lowering agent, antiplatelet agent, smoking
  7. Model 6: adjusted for age, sex, systolic BP, fasting glucose, HDL, CRP, anti-hypertension medication, antidiabetic medication, lipid lowering agent, antiplatelet agent, smoking, physical activity
  8. CI confidence interval, NWO normal weight obesity, NWL normal weight lean, PWV pulse wave velocity