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Table 2 Multiple logistic regression models for associations between clinical and biochemical variables and the progression of diabetic nephropathy in a total of 154 subjects with T1D

From: Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes

 

Model 1

Model 2

Model 3

 

(R 2  = 0.28)

(R 2  = 0.20)

(R 2  = 0.28)

Variables

OR

95 % CI

P

OR

95 % CI

P

OR

95 % CI

P

Age, per year

1.03

0.99–1.07

0.132

1.03

0.99–1.06

0.188

1.03

0.99–1.07

0.136

Obesity (0 = no, 1 = yes)

1.92

0.64–5.78

0.243

1.95

0.69–5.55

0.210

1.94

0.64–5.81

0.242

Duration of diabetes, per 5years

1.44

1.01–2.07

0.047

1.28

0.92–1.77

0.145

1.44

1.01–2.07

0.047

Hypertension (0 = no, 1 = yes)

2.32

0.77–6.99

0.134

2.09

0.79–5.83

0.160

2.32

0.77–6.98

0.136

Albuminuria at baseline (0 = no, 1 = yes)

2.63

1.03–6.73

0.043

2.86

1.16–7.07

0.023

2.64

1.03–6.74

0.043

Statin use (0 = no, 1 = yes)

1.89

0.74–4.88

0.186

1.49

0.59–3.75

0.403

1.91

0.73–5.01

0.188

CKD stage at baseline

         

 Stage1

Reference

Reference

Reference

 Stage2

0.55

0.16–1.86

0.338

0.71

0.23–2.24

0.559

0.55

0.16–1.86

0.337

 Stage3 and 4

0.09

0.01–1.30

0.078

0.12

0.01–1.54

0.103

0.09

0.01–1.31

0.078

mean GA (%)*

2.02

1.28–3.17

0.002

   

2.03

1.27–3.26

0.003

mean HbA1c (%)*

   

1.21

0.79–1.85

0.390

0.98

0.62–1.54

0.918

  1. CKD chronic kidney disease
  2. *z-standardization of glycemic indices