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Table 1 Demographic and laboratory characteristics of patients

From: Glycated albumin and the risk of micro- and macrovascular complications in subjects with Type 1 Diabetes

  All Group I Group II
   DN progression DN non-progression P
  (n = 154) (n = 30) (n = 124)  
Demographics     
Age (years) 46 ± 15 50 ± 15 45 ± 16 0.135
Male Sex, n (%) 69 (45) 11 (37) 58 (47) 0.414
BMI (kg/m2) 22.6 ± 3.3 23.2 ± 3.5 22.4 ± 3.3 0.256
Obesity, n (%) 30 (19) 8 (27) 22 (18) 0.306
Duration of diabetes (years) 10.0 (3.0–15.0) 12.0 (10.0–18.0) 8.0 (3.0–15.0) 0.004
Retinopathy, n (%) 78 (51) 21 (70) 57 (46) 0.018
Hypertension, n (%) 31 (20) 9 (30) 22 (18) 0.202
ARB or ACEI use, n (%) 49 (32) 11 (37) 38 (31) 0.663
Statin use, n (%) 54 (35) 15 (50) 39 (31) 0.056
Glycemic indices
mean GA (%) 24.4 (21.5–29.0) 29.3 (22.8–34.7) 24.0 (21.0–27.5) 0.004
mean HbA1c (%) 8.7 ± 1.6 9.0 ± 1.4 8.7 ± 1.7 0.088
Renal function indices
Baseline ACR (μg/mg) 17.8 (7.2–71.1) 47.3 (11.5–136.1) 14.6 (6.0–41.2) 0.004
Follow-up ACR (μg/mg) 13.8 (7.5–77.9) 134.7 (51.7–766.2) 10.6 (6.8–29.2) <0.001
Baseline eGFR (mL/min/1.73 m2) 97.1 ± 22.5 91.7 ± 20.3 98.4 ± 22.9 0.079
Follow-up eGFR (mL/min/1.73 m2) 95.1 ± 26.0 73.9 ± 28.7 100.4 ± 22.4 <0.001
Baseline CKD status
 Stage 1 98 (64) 17 (57) 81 (65) 0.565
 Stage 2 48 (31) 12 (40) 36 (29)
 Stage 3 and 4 8 (5) 1 (3) 7 (6)
Biochemistry profiles
Albumin (g/dL) 4.2 ± 0.4 4.1 ± 0.5 4.3 ± 0.4 0.106
Total cholesterol (mg/dL) 162.0 (145.0–194.0) 171.5 (149.0–195.8) 162.0 (144.0–193.5) 0.423
Triglyceride (mg/dL) 79.0 (60.0–113.5) 90.5 (71.8–118.5) 77.0 (57.0–114.0) 0.109
HDL-cholesterol (mg/dL) 57.0 ± 15.9 55.0 ± 13.7 57.5 ± 16.4 0.669
LDL-cholesterol (mg/dL) 95.5 ± 34.9 97.6 ± 31.3 95.0 ± 35.8 0.495
  1. Continuous variables were described as median (quartiles) or mean ± SD. N (%) for categorical variables
  2. BMI body mass index; ARB angiotensin II receptor blocker, ACEI angiotensin-converting enzyme inhibitor, ACR albumin-creatinine ratio, eGFR estimated glomerular filtration rate, CKD chronic kidney disease