Fig. 2

Effect of transient cerebral ischemia on cognitive function and brain injury in non-diabetic mice versus diabetic mice. Cognitive function was estimated by Morris water maze test. a, b, c, and d indicate escape latency of the hidden platform test on 4 consecutive days (1–20 sessions), escape latency in the visible test, brain weight, and cerebral blood flow, respectively, in non-diabetic mice. Each value represents mean ± SEM (n = 6 in Sham, n = 5 in BCCAO). e, f, g, and h indicate escape latency of the hidden platform test on 4 consecutive days (1–20 sessions), escape latency in the visible test, brain weight, and cerebral blood flow, respectively, in diabetic mice. Each value represents mean ± SEM (n = 6 in Sham, n = 5 in BCCAO). Abbreviations used: Sham, sham-operated group; BCCAO, group subjected to bilateral common carotid arterial occlusion