Increased plasma BMP-2 levels are associated with atherosclerosis burden and coronary calcification in type 2 diabetic patients

Table 2 Association between BMP-2 with type II diabetes mellitus and coronary artery disease after adjusting for traditional cardiovascular risk factors

Variable	Estimate	Standard error	P
Age (Increase by 1 year)	0.57	0.42	0.19
Male gender	−0.032	0.07	0.68
Body mass index	−0.01	0.009	0.30
Hypertension	−0.11	0.08	0.18
Dyslipidemia	−0.006	0.08	0.94
Smoking	−0.051	0.08	0.50
Random blood glucose, mmol/L (Increase by 1 mmol/L)	0.12	0.05	0.027
Hs-CRP, mg/L (Increase by 1 mg/L)	0.33	0.19	0.08
HbA1c (n %) (Increase by 1%)	0.17	0.06	0.0079
T2DM	−0.39	0.11	0.0002
CAD	−0.26	0.09	0.004

Data are expressed as parameter estimates with standard errors. CAD, Coronary artery disease; HbA1C, glycosylated hemoglobin A1C; Hs-CRP, Highly sensitive C-reactive protein; T2DM, Type II diabetes mellitus.

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