Elevated plasma BMP-2 levels are associated with the presence of DM and CAD. Bars represent average plasma BMP-2 levels amongst patients in each group. T-bars indicate standard deviation. Groups are as follows: 1; patients without CAD or T2DM, 2; patients with T2DM only; 3, patients with CAD only and 4, patients with T2DM and CAD. (*p < 0.05 as compared to group without CAD and T2DM; # p < 0.05 as compared to group with CAD only).