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Table 4 Interactive effects between the GGT1 genotype and serum HDL-C levels on the baPWV in the T2DM subjects

From: Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy

HDL-C GGT1 genotype High baPWV * baPWV (cm/sec)
OR (95% CI) P -value B SE P -value
≥ 1.0 mmol/L A/A genotype 1 - 0 - -
  A/G or G/G genotype 1.49 (0.91 - 2.44) 0.11 47.38 38.60 0.22
<1.0 mmol/L A/A genotype 1.31 (0.73 - 2.35) 0.37 58.32 54.50 0.29
  A/G or G/G genotype 2.49 (1.07 - 5.82) 0.04 150.84 79.19 0.06
  1. Bold typeface indicates data that are statistically significant.
  2. *baPWV ≥ 1750 cm/sec.
  3. Adjusted by age, hypertension, diabetes duration, drinking, ALT level and ALDH2*2 allele.
  4. GGT, γ-glutamyltransferase; HDL-C, high-density lipoprotein cholesterol; baPWV, brachial-ankle pulse wave velocity; T2DM, type 2 diabetes mellitus; OR, odds ratio; CI, confidence interval; B, partial regression coefficient; SE, standard error.