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Table 3 Association between a high baPWV (≥1,750 cm/sec) and the covariates in the T2DM subjects

From: Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy

 

High baPWV

Univariate

Multivariate

OR (95% CI)

P -value

OR (95% CI)

P -value

GGT1 G allele

1.80 (1.16 - 2.78)

0.008

1.54 (0.97 - 2.43)

0.07

Age

1.11 (1.08 - 1.14)

< 0.001

1.10 (1.07 - 1.13)

< 0.001

Hypertension

3.84 (2.47 - 5.98)

< 0.001

3.37 (2.11 - 5.38)

< 0.001

Diabetes duration

1.06 (1.03 - 1.08)

< 0.001

1.02 (0.997 - 1.05)

0.09

HDL-C < 1.0 mmol/L

1.71 (1.07 - 2.74)

0.03

1.40 (0.87 - 2.26)

0.16

Drinking

0.63 (0.42 - 0.94)

0.02

1.06 (0.66 - 1.69)

0.83

ALT

0.99 (0.98 - 1.00)

0.07

1.01 (0.99 - 1.02)

0.40

ALDH2*2 allele

1.43 (0.94 - 2.20)

0.099

1.47 (0.90 - 2.40)

0.13

GGT

1.00 (0.995 - 1.01)

0.60

  

Female

1.18 (0.75 - 1.85)

0.49

  

BMI

0.99 (0.93 - 1.05)

0.76

  

HbA1c

0.94 (0.84 - 1.05)

0.26

  

AST

1.01 (0.99 - 1.03)

0.52

  

LDL-C ≥ 3.6 mmol/L

0.84 (0.57 - 1.23)

0.37

  

Triglycerides ≥ 1.7 mmol/L

1.14 (0.77 - 1.69)

0.51

  
  1. Bold typeface indicates data that are statistically significant. baPWV, brachial-ankle pulse wave velocity; T2DM, type 2 diabetes mellitus; OR, odds ratio; CI, confidence interval; GGT, γ-glutamyltransferase; HDL-C, high-density lipoprotein cholesterol; ALT, alanine aminotransferase; ALDH2, aldehyde dehydrogenase 2; BMI, body mass index; HbA1c, hemoglobin A1c; AST, aspartate aminotransferase; LDL-C, low-density lipoprotein cholesterol.
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Cardiovascular Diabetology

ISSN: 1475-2840