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Table 3 Association between a high baPWV (≥1,750 cm/sec) and the covariates in the T2DM subjects

From: Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy

  High baPWV
Univariate Multivariate
OR (95% CI) P -value OR (95% CI) P -value
GGT1 G allele 1.80 (1.16 - 2.78) 0.008 1.54 (0.97 - 2.43) 0.07
Age 1.11 (1.08 - 1.14) < 0.001 1.10 (1.07 - 1.13) < 0.001
Hypertension 3.84 (2.47 - 5.98) < 0.001 3.37 (2.11 - 5.38) < 0.001
Diabetes duration 1.06 (1.03 - 1.08) < 0.001 1.02 (0.997 - 1.05) 0.09
HDL-C < 1.0 mmol/L 1.71 (1.07 - 2.74) 0.03 1.40 (0.87 - 2.26) 0.16
Drinking 0.63 (0.42 - 0.94) 0.02 1.06 (0.66 - 1.69) 0.83
ALT 0.99 (0.98 - 1.00) 0.07 1.01 (0.99 - 1.02) 0.40
ALDH2*2 allele 1.43 (0.94 - 2.20) 0.099 1.47 (0.90 - 2.40) 0.13
GGT 1.00 (0.995 - 1.01) 0.60   
Female 1.18 (0.75 - 1.85) 0.49   
BMI 0.99 (0.93 - 1.05) 0.76   
HbA1c 0.94 (0.84 - 1.05) 0.26   
AST 1.01 (0.99 - 1.03) 0.52   
LDL-C ≥ 3.6 mmol/L 0.84 (0.57 - 1.23) 0.37   
Triglycerides ≥ 1.7 mmol/L 1.14 (0.77 - 1.69) 0.51   
  1. Bold typeface indicates data that are statistically significant. baPWV, brachial-ankle pulse wave velocity; T2DM, type 2 diabetes mellitus; OR, odds ratio; CI, confidence interval; GGT, γ-glutamyltransferase; HDL-C, high-density lipoprotein cholesterol; ALT, alanine aminotransferase; ALDH2, aldehyde dehydrogenase 2; BMI, body mass index; HbA1c, hemoglobin A1c; AST, aspartate aminotransferase; LDL-C, low-density lipoprotein cholesterol.