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Table 2 Factors associated with the serum GGT levels stratified by the GGT1 genotype in the general subjects in the univariate regression model

From: Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy

  GGT (IU/L)
GGT1 A/A genotype GGT1 A/G or G/G genotype
B SE P -value B SE P -value
Fatty liver 24.61 5.24 <0.001 20.67 5.16 <0.001
Dyslipidemia 11.08 4.34 0.01 15.16 4.73 0.001
Ever smoking 19.68 4.31 <0.001 16.66 4.72 <0.001
Drinking 18.13 4.30 <0.001 15.94 4.70 0.001
ALDH2*2 allele −12.60 4.43 0.005 −5.90 4.80 0.22
BMI 3.76 0.70 <0.001 2.13 0.76 0.006
AST 3.24 0.17 <0.001 2.09 0.36 <0.001
ALT 1.67 0.14 <0.001 1.62 0.20 <0.001
HbA1c 8.07 1.81 <0.001 6.50 2.66 0.02
Systolic BP 0.27 0.13 0.04 0.35 0.15 0.02
Diastolic BP 0.84 0.20 <0.001 0.65 0.23 0.005
Triglycerides 0.16 0.03 <0.001 0.28 0.03 <0.001
Fasting plasma glucose 0.22 0.12 0.06 0.53 0.15 0.001
HDL-C 0.05 0.13 0.68 −0.38 0.14 0.005
LDL-C 0.001 0.09 0.99 0.18 0.09 0.04
  1. Bold typeface indicates data that are significant only in the G allele carriers.
  2. GGT, γ-glutamyltransferase; B, partial regression coefficient; SE; standard error; ALDH2, aldehyde dehydrogenase 2; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; HbA1c, hemoglobin A1c; BP, blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.