| |
A/A (n = 219)
|
A/G (n = 120)
|
G/G (n = 13)
|
P
-value
|
|---|
|
Female (%)
|
33.3
|
35.0
|
46.2
|
0.61
|
|
Age (years)
|
59.1 ± 10.5
|
61.6 ± 11.7
|
60.0 ± 10.6
|
0.13
|
|
BMI (kg/m2)
|
24.3 ± 3.9
|
24.0 ± 3.4
|
24.1 ± 2.9
|
0.72
|
|
Diabetes duration (years)
|
10.7 ± 8.2
|
10.7 ± 8.8
|
10.8 ± 6.2
|
1.00
|
|
HbA1c (%)
|
8.4 ± 2.0
|
8.3 ± 2.0
|
8.1 ± 2.0
|
0.66
|
|
Systolic BP (mmHg)
|
139.5 ± 19.5
|
137.9 ± 21.3
|
143.4 ± 17.2
|
0.57
|
|
Diastolic BP (mmHg)
|
83.4 ± 11.4
|
81.8 ± 12.9
|
85.9 ± 9.7
|
0.31
|
|
Triglycerides (mmol/L)
|
1.7 ± 1.2
|
1.9 ± 2.3
|
1.8 ± 1.9
|
0.50
|
|
HDL-C (mmol/L)
|
1.4 ± 0.4
|
1.4 ± 0.4
|
1.4 ± 0.3
|
1.00
|
|
LDL-C (mmol/L)
|
3.2 ± 0.8
|
3.2 ± 0.9
|
3.1 ± 0.6
|
0.90
|
|
AST (IU/L)
|
24.8 ± 9.7
|
27.1 ± 14.2
|
25.2 ± 8.4
|
0.22
|
|
ALT (IU/L)
|
26.6 ± 16.4
|
30.2 ± 27.2
|
27.7 ± 11.6
|
0.31
|
|
GGT (IU/L)
|
36.6 ± 33.1
|
42.2 ± 36.8
|
43.6 ± 24.1
|
0.31
|
|
Log GGT (IU/L)
|
1.47 ± 0.30
|
1.51 ± 0.30
|
1.57 ± 0.26
|
0.08
|
|
Hypertension (%)
|
60.3
|
59.2
|
76.9
|
0.50
|
|
Dyslipidemia (%)
|
68.8
|
70.8
|
38.5
|
0.07
|
|
Ever smoker (%)
|
45.4
|
41.2
|
33.3
|
0.70
|
|
Alcohol intake (%)
|
51.4
|
46.7
|
38.5
|
0.52
|
|
Therapy components
| | | | |
|
Hypoglycemic agents
| | | | |
|
Oral hypoglycemic agents (%)
|
64.1
|
65.5
|
53.8
|
0.72
|
|
Insulin (%)
|
23.0
|
19.3
|
30.8
|
0.52
|
|
Antihypertensive agents
| | | | |
|
ACE inhibitors or ARBs(%)
|
20.3
|
16.0
|
7.7
|
0.44
|
|
Others(%)
|
23.5
|
26.9
|
23.1
|
0.77
|
|
Agents for hyperlipidemia
| | | | |
|
Fibrates(%)
|
0.9
|
0.8
|
7.7
|
0.15
|
|
Statins(%)
|
8.3
|
6.7
|
0.0
|
0.70
|
|
Others (%)
|
0.9
|
1.7
|
0.0
|
0.67
|
- Data are percentages or mean ± standard deviation.
- T2DM, type 2 diabetes mellitus; GGT, γ-glutamyltransferase; BMI, body mass index; HbA1c, hemoglobin A1c; BP, blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ACE, angiotensin converting enzyme; ARB, angiotensin II receptor blocker.
