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Figure 5 | Cardiovascular Diabetology

Figure 5

From: Skeletal muscle insulin resistance in salt-sensitive hypertension: role of angiotensin II activation of NFκB

Figure 5

The protein expression of phospho (Ser 612)-insulin receptor substance 1 (IRS1, A), phospho (Ser 473) Akt (B) and Glut-4 in membrane fraction (C) in the soleus muscle of DS rats. The protein expression of phospho (Ser 612)-IRS1 was increased, and phospho (Ser 473) Akt and Glut-4 in the membrane fraction was significantly decreased in hypertensive DS rats, which was restored by the treatment of either ARB, tempol or PDTC treatment. *P < 0.05 vs. NS, #p < 0.05 vs. HS; N = 4-5.

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