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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Skeletal muscle insulin resistance in salt-sensitive hypertension: role of angiotensin II activation of NFκB

Figure 2

Superoxide (O2 -) production (A) and the mRNA expression of nicotinamide adenine dinucleotide phosphate (reduced form, NADPH) oxidase subunits p22phox (B) and gp91phox (C) in the soleus of DS rats. O2 - production and the expression of p22phox and gp91phox were significantly increased in the muscle of hypertensive DS rats, compared with normotensive DS rats. ARB candesartan significantly reduced O2 - production and the mRNA expression of p22phox and gp91phox . *P < 0.05 vs. NS, #p < 0.05 vs. HS; N = 5-7.

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