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Table 3 HRs of death, MI and IS/TIA associated with eGFR category

From: Cardiovascular events and all-cause mortality in a cohort of 57,946 patients with type 2 diabetes: associations with renal function and cardiovascular risk factors

  Death MI IS/TIA
HR a (95% CI) HR a (95% CI) HR a (95% CI)
eGFR calculated with the MDRD study equation, mL/min
15–29 2.79 (2.57–3.03) 2.34 (1.90–2.88) 1.78 (1.44–2.19)
30–59 1.38 (1.33-1.43) 1.37 (1.27-1.48) 1.13 (1.05-1.22)
  30–44 1.83 (1.74–1.92) 1.75 (1.56–1.97) 1.27 (1.13–1.43)
  45–59 1.25 (1.20–1.30) 1.27 (1.17–1.38) 1.09 (1.01–1.18)
≥60 1 (−) 1 (−) 1 (−)
eGFR calculated with the CKD-EPI equation, mL/min
15–29 2.79 (2.59–2.99) 2.21 (1.83–2.66) 1.73 (1.44–2.09)
30–59 1.41 (1.36-1.46) 1.38 (1.28-1.49) 1.20 (1.12-1.29)
  30–44 1.75 (1.67–1.84) 1.72 (1.54–1.92) 1.28 (1.15–1.43)
  45–59 1.29 (1.24–1.34) 1.27 (1.17–1.38) 1.19 (1.09–1.27)
≥60 1 (−) 1 (−) 1 (−)
  1. aAdjusted for sex, age at start date, duration of diabetes, BMI, smoking status, number of medications, HbA1c level, presence of hypertension hyperlidemia, and history of MI, IS/TIA and IHD.
  2. BMI, body mass index; CI, confidence interval; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; HR, hazard ratio; IHD, ischemic heart disease; IS, ischemic stroke; MI, myocardial infarction; TIA, transient ischemic attack.