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Table 1 Baseline characteristics, overall and according to estimated glomerular filtration rate category

From: Cardiovascular events and all-cause mortality in a cohort of 57,946 patients with type 2 diabetes: associations with renal function and cardiovascular risk factors

   eGFR category (mL/min)
  Overall (N = 57,946) 15–29 (n = 972) 30–44 (n = 4326) 45–59 (n = 12,614) ≥ 60 (n = 40,034)
  Number % Number % Number % Number % Number %
Sex
  Men 32,117 55.4 315 32.4 1654 38.2 5434 43.1 24,714 61.7
  Women 25,829 44.6 657 67.6 2672 61.8 7180 56.9 15,320 38.3
Age at start date (years)
  20–39 1269 2.2 0 0.0 3 0.1 30 0.2 1236 3.1
  40–49 4454 7.7 8 0.8 27 0.6 187 1.5 4232 10.6
  50–59 10,729 18.5 37 3.8 175 4.0 1067 8.5 9450 23.6
  60–69 17,889 30.9 196 20.2 883 20.4 3623 28.7 13,187 32.9
  70–79 16,933 29.2 378 38.9 1882 43.5 5303 42.0 9370 23.4
  80–89 6672 11.5 353 36.3 1356 31.3 2404 19.1 2559 6.4
Smoking status
  Non-smoker 30,175 52.1 561 57.7 2441 56.4 7028 55.7 20,145 50.3
  Current 10,128 17.5 104 10.7 533 12.3 1671 13.2 7820 19.5
  Former 15,011 25.9 240 24.7 1105 25.5 3367 26.7 10,299 25.7
  Unknown 2632 4.5 67 6.9 247 5.7 548 4.3 1770 4.4
BMI (kg/m2)
  15–19 915 1.6 18 1.9 84 1.9 234 1.9 579 1.4
  20–24 9546 16.5 174 17.9 818 18.9 2223 17.6 6331 15.8
  25–29 21,011 36.3 297 30.6 1521 35.2 4757 37.7 14,436 36.1
  ≥ 30 22,959 39.6 362 37.2 1487 34.4 4529 35.9 16,581 41.4
  Unknown 3515 6.1 121 12.4 416 9.6 871 6.9 2,107 5.3
Number of drugs
  ≤1 15,007 25.9 107 11.0 626 14.5 2708 21.5 11,566 28.9
  2–4 20,458 35.3 224 23.0 1185 27.4 4121 32.7 14,928 37.3
  5–9 18,680 32.2 461 47.4 1920 44.4 4748 37.6 11,551 28.9
  10–14 3335 5.8 158 16.3 513 11.9 906 7.2 1758 4.4
  ≥15 466 0.8 22 2.3 82 1.9 131 1.0 231 0.6
Duration of diabetes (years)
  <1 2848 4.9 26 2.7 138 3.2 557 4.4 2127 5.3
  1–4 23,201 40.0 208 21.4 1311 30.3 4545 36.0 17,137 42.8
  5–9 17,123 29.5 298 30.7 1271 29.4 3786 30.0 11,768 29.4
  10–14 8503 14.7 184 18.9 824 19.0 2095 16.6 5400 13.5
  ≥15 6271 10.8 256 26.3 782 18.1 1631 12.9 3602 9.0
HbA1c (%)
  <7.00 19,382 33.4 272 28.0 1463 33.8 4480 35.5 13,167 32.9
  7.00–7.99 12,823 22.1 203 20.9 964 22.3 2922 23.2 8734 21.8
  8.00–8.99 7221 12.5 111 11.4 480 11.1 1565 12.4 5065 12.7
  9.00–9.99 4634 8.0 66 6.8 302 7.0 877 7.0 3389 8.5
  10.00–10.99 2497 4.3 44 4.5 142 3.3 433 3.4 1878 4.7
  ≥11 2301 4.0 43 4.4 134 3.1 409 3.2 1715 4.3
  Missing 9088 15.7 233 24.0 841 19.4 1928 15.3 6086 15.2
PCP visits
  0–4 8018 13.8 87 9.0 471 10.9 1508 12.0 5952 14.9
  5–9 17,371 30.0 229 23.6 1120 25.9 3640 28.9 12,382 30.9
  10–19 23,024 39.7 355 36.5 1717 39.7 5228 41.4 15,724 39.3
  ≥20 9533 16.5 301 31.0 1018 23.5 2238 17.7 5976 14.9
Referrals
  0–4 50,987 88.0 750 77.2 3634 84.0 10,976 87.0 35,627 89.0
  5–9 5525 9.5 162 16.7 513 11.9 1287 10.2 3563 8.9
  10–19 1315 2.3 55 5.7 162 3.7 325 2.6 773 1.9
  ≥20 119 0.2 5 0.5 17 0.4 26 0.2 71 0.2
Hospitalizations
  None 52,092 89.9 735 75.6 3676 85.0 11,206 88.8 36,475 91.1
  1–2 5013 8.7 176 18.1 524 12.1 1190 9.4 3123 7.8
  ≥3 841 1.5 61 6.3 126 2.9 218 1.7 436 1.1
Townsend deprivation index
  1 (least deprived) 11,719 20.2 146 15.0 752 17.4 2445 19.4 8376 20.9
  2 11,797 20.4 173 17.8 811 18.7 2515 19.9 8298 20.7
  3 11,672 20.1 214 22.0 884 20.4 2586 20.5 7988 20.0
  4 11,548 19.9 223 22.9 958 22.1 2486 19.7 7881 19.7
  5 (most deprived) 8203 14.2 155 15.9 682 15.8 1875 14.9 5491 13.7
  Unknown 3007 5.2 61 6.3 239 5.5 707 5.6 2000 5.0
Practice location
  Urban 38,467 66.4 628 64.6 2862 66.2 8,443 66.9 26,534 66.3
  Town 6335 10.9 114 11.7 476 11.0 1,207 9.6 4,538 11.3
  Rural 3373 5.8 55 5.7 239 5.5 703 5.6 2,376 5.9
  Unknown 9771 16.9 175 18.0 749 17.3 2,261 17.9 6,586 16.5
  1. BMI, body mass index; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; PCP, primary care physician.