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Table 3 Multivariate linear regression analyses for variables independently associated with waist circumference for both polymorphisms (rs8192673 of the PGC - gene, rs1801282 of the PPAR - γ )

From: Polymorphisms of the Peroxisome Proliferator-Activated Receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus

rs8192673 of the PGC - gene

 

β

p

Age (year)

−0.09

<0.001

Gender (0 = male, 1 = female)

−1.179

0.019

Triglycerides (mmol/L)

0.684

<0.001

LDL cholesterol (mmol/L)

0.288

0.759

HbA1c (%)

0.013

0.957

Insulin therapy (0 = no, 1 = yes)

−0.864

0.101

Hypolipemic therapy (0 = no, 1 = yes)

−0.479

0.786

TC*

0.537

0.271

CC*

0.646

0.54

rs1801282 of the PPAR - γ

Age (year)

−0.007

0.807

Gender (0 = male, 1 = female)

−1.213

0.016

Triglycerides (mmol/L)

−0.698

<0.001

LDL cholesterol (mmol/L)

−0.269

0.759

HbA1c (%)

0.134

0.954

Insulin therapy (0 = no, 1 = yes)

−0.812

0.122

Hypolipemic therapy (0 = no, 1 = yes)

0.550

0.755

CG**

−0.673

0.024

GG**

−0.832

0.035

  1. *Reference genotype was TT; **Reference genotype was CC.