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Table 5 Effects of MK-0626 plus GLP-1 on urine pH

From: Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

 

Baseline

Treatment

MK-0626 + saline

6.07 ± 0.17

6.25 ± 0.20

MK-0626 + GLP-1 2.4 pmol/kg/min

6.09 ± 0.14

6.93 ± 0.14*

MK-0626 + GLP-1 4.8 pmol/kg/min

6.03 ± 0.11

6.92 ± 0.12**

MK-0626 + GLP-1 9.6 pmol/kg/min

6.19 ± 0.11

6.90 ± 0.07**

  1. *P < 0.05, **p < 0.01 vs. baseline. Baseline refers to the 20 minutes period prior to IV administration of saline or MK-0626.
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Cardiovascular Diabetology

ISSN: 1475-2840