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Table 3 Effects of Liraglutide (at the end of the study) on renal function, blood glucose and insulin

From: Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

 

Saline

Liraglutide

 

Baseline

Treatment

Baseline

Treatment

GFR (ml/min/kw(g))

1.3 ± 0.16

1.5 ± 0.21

0.9 ± 0.09

1.4 ± 0.05*

RBF (ml/min/kw(g))

8.3 ± 0.49

10.5 ± 1.18

6.8 ± 0.99

8.4 ± 1.38

Glucose (mg/dl)

132.3 ± 3.33

140.4 ± 5.6

144.9 ± 4.2

168.9 ± 10.7*

Insulin (ng/ml)

2.2 ± 0.25

3.1 ± 0.62

3.0 ± 0.5

3.6 ± 0.7

  1. *P < 0.05 post- vs. pre-treatment (baseline). Baseline refers to the 20 minutes period prior to administration of saline or Liraglutide.