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Table 3 Effects of Liraglutide (at the end of the study) on renal function, blood glucose and insulin

From: Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

  Saline Liraglutide
  Baseline Treatment Baseline Treatment
GFR (ml/min/kw(g)) 1.3 ± 0.16 1.5 ± 0.21 0.9 ± 0.09 1.4 ± 0.05*
RBF (ml/min/kw(g)) 8.3 ± 0.49 10.5 ± 1.18 6.8 ± 0.99 8.4 ± 1.38
Glucose (mg/dl) 132.3 ± 3.33 140.4 ± 5.6 144.9 ± 4.2 168.9 ± 10.7*
Insulin (ng/ml) 2.2 ± 0.25 3.1 ± 0.62 3.0 ± 0.5 3.6 ± 0.7
  1. *P < 0.05 post- vs. pre-treatment (baseline). Baseline refers to the 20 minutes period prior to administration of saline or Liraglutide.