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Table 2 Hazard ratios for mortality associated with elevated body mass index in patients with and without diabetes

From: Association of obesity and long-term mortality in patients with acute myocardial infarction with and without diabetes mellitus: results from the MONICA/KORA myocardial infarction registry

 

No diabetes (n=2864)

Diabetes (n=1190)

HR [95% CI]

p-value

HR [95% CI]

p-value

Unadjusted model

Normal weight

1.0

 

1.0

 

Overweight

0.74 [0.59-0.93]

0.0097

0.76 [0.56-1.02]

0.0707

Obesity

0.62 [0.46-0.85]

0.0023

0.79 [0.58-1.09]

0.1495

Minimal modela

Normal weight

1.0

 

1.0

 

Overweight

0.72 [0.57-0.90]

0.0040

0.80 [0.59-1.08]

0.1467

Obesity

0.64 [0.47-0.86]

0.0036

0.91 [0.77-1.31]

0.5691

Parsimonious model

Normal weight

1.0

 

1.0

 

Overweight

0.73 [0.58-0.93]b

0.0087

0.83 [0.61-1.13]c

0.2383

Obesity

0.64 [0.47-0.87]b

0.0043

0.98 [0.71-1.36]c

0.8914

  1. HR=Hazard Ratio, CI=Confidence Interval, BMI=Body Mass Index.
  2. aAdjusted for sex and age.
  3. bAdjusted for sex, age, stroke, smoking, re-infarction, left ventricular ejection fraction (<30% versus ≥30%), any reperfusion treatment (coronary artery bypass surgery, percutaneous coronary intervention (PCI) or thrombolysis), beta-blockers (medication prior AMI), all four medications at discharge (antiplatelet agents, beta-blockers, ACEIs/ARBs (Angiotensin-converting enzyme inhibitors/Angiotensin receptor blockers), statins).
  4. cAdjusted for sex, age, hyperlipidemia, re-infarction, any reperfusion treatment, statins (medication prior AMI), all four medications at discharge.