Variable | Controls | NAFLD | Type 2 diabetes | P value |
---|---|---|---|---|
(n = 19) | (n = 19) | (n = 19) | ||
Age (yr) | 56 ± 14 | 54 ± 15 | 62 ± 8 | 0.127 |
Gender (men:women) | 11:8 | 11:8 | 11:8 | - |
Height (cm) | 169 ± 11 | 169 ± 9 | 168 ± 9 | 0.877 |
Weight (kg) | 78 ± 11 | 83 ± 14 | 91 ± 14* | 0.013 |
BMI (kg/m2) | 28 ± 4 | 29 ± 3* | 33 ± 5* | 0.012 |
Body surface area (m2) | 1.9 ± 0.2 | 1.9 ± 0.2 | 2.0 ± 0.2* | 0.018 |
Visceral adipose tissue (cm2) | - | 154 ± 47 | 191 ± 75 | 0.120 |
Systolic blood pressure (mmHg) | 131 ± 11 | 146 ± 16* | 145 ± 17* | 0.003 |
Diastolic blood pressure (mmHg) | 82 ± 8 | 90 ± 12 | 89 ± 12 | 0.096 |
VO2peak (ml min−1 kg−1) | - | 24 ± 6 | 19 ± 5†| 0.007 |
Fasting Glucose (mmol/L) | 5.2 ± 0.5 | 5.0 ± 0.6 | 7.2 ± 1.4*†| 0.000 |
HbA1c (mmol/mol) | - | 38 ± 5 | 58 ± 10†| 0.000 |
(%) |  | (5.6 ± 0.4) | (7.4 ± 0.9) |  |
Intrahepatic lipid (%) | 2.5 ± 0.9 | 9.4 ± 4.3* | 7.9 ± 6.7* | 0.000 |
ALT (U.L) | 23 ± 12 | 51 ± 39* | 30 ± 11 | 0.013 |
Total cholesterol (mmol/L) | 5.3 ± 0.7 | 5.1 ± 1.2 | 4.7 ± 1.4 | 0.342 |
Triglycerides (mmol/L) | 1.7 ± 0.9 | 1.5 ± 0.8 | 1.3 ± 1.1 | 0.328 |
Medications | Â | Â | Â | - |
Statins | 0 | 4 | 10 | Â |
Blood pressure | 0 | 1 | 8 | Â |
Metformin | 0 | 0 | 12 | Â |