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Table 1 Effects of diabetes and candesartan on weight gain, blood glucose and SABP

From: Candesartan restores pressure-induced vasodilation and prevents skin pressure ulcer formation in diabetic mice

Groups

Control

Diabetic

Candesartan

Diabetic + Candesartan

Body weight gain (g)

22.25 ± 0.86

4.94 ± 1.10***

19.25 ± 2.20

10.25 ± 1.36***

Blood glucose (mg/dL)

130.3 ± 7.94

466.7 ± 39.08

120.5 ± 5.09

461.4 ± 44.04

SABP (mmHg)

64.33 ± 3.38

73.58 ± 5.88

66.71 ± 4.93

64.92 ± 4.28

  1. SABP: systolic arterial blood pressure. (n = 10 in each group, 1-way ANOVA followed by Newman-Keuls’s post-hoc test, ***P < 0.001: significance of the difference between candesartan-treated mouse group and respective untreated mouse group).