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Table 5 Adjusted associations of glucose and triglyceride excursions (of 25 mg/dL) with clinical outcomes (n = 898)

From: Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study

Glucose excursion

Model

Global

Obese (n=375)

Non-obese (n=523)

Interaction

  

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

p

Any cardiovascular complication

1

1.15

(1.06-1.25)

<0.01

1.19

(1.01-1.39)

0.04

1.15

(1.03-1.27)

0.01

0.86

2

1.06

(0.95-1.17)

0.32

1.12

(0.92-1.36)

0.26

1.03

(0.89-1.19)

0.94

0.35

  Heart disease

1

1.13

(1.03-1.25)

0.01

1.22

(1.03-1.46)

0.02

1.10

(0.98-1.25)

0.11

0.38

2

1.04

(0.91-1.18)

0.57

1.20

(0.96-1.50)

0.12

0.96

(0.82-1.14)

0.65

0.11

  Myocardial infarction

1

1.21

(1.06-1.38)

<0.01

1.32

(1.03-1.68)

0.03

1.17

(1.00-1.36)

0.05

0.42

  Angina

1

1.11

(0.99-1.25)

0.09

1.21

(0.99-1.48)

0.06

1.07

(0.92-1.25)

0.41

0.36

  Stroke

1

1.23

(1.02-1.48)

0.03

1.08

(0.63-1.84)

0.78

1.25

(1.-1.47)

0.05

0.50

  Heart failure

1

1.15

(1.00-1.33)

0.06

1.19

(0.93-1.52)

0.16

1.15

(0.95-1.38)

0.15

0.90

Triglyceride excursion

 

Global

Obese (n=375)

Non-obese (n=523)

Interaction

  

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

p

Any cardiovascular complication

1

1.00

(0.90-1.12)

0.94

1.11

(0.91-1.35)

0.32

0.93

(0.81-1.08)

0.34

0.15

2

1.01

(0.90-1.13)

0.87

1.15

(0.93-1.43)

0.20

0.91

(0.78-1.06)

0.21

0.06

  Heart disease

1

1.02

(0.89-1.16)

0.80

1.23

(0.96-1.58)

0.10

0.91

(0.78-1.07)

0.24

0.04

2

1.02

(0.90-1.17)

0.72

1.25

(0.95-1.63)

0.11

0.91

(0.77-1.07)

0.24

0.04

  Myocardial infarction

1

1.07

(0.87-1.32)

0.52

1.12

(0.79-1.59)

0.53

1.05

(0.80-1.36)

0.73

0.79

  Angina

1

1.01

(0.85-1.19)

0.93

1.36

(1.01-1.83)

0.04

0.86

(0.72-1.02)

0.09

0.01

  Stroke

1

0.96

(0.76-1.21)

0.75

0.89

(0.64-1.24)

0.49

0.98

(0.72-1.33)

0.92

0.76

  Heart failure

1

1.03

(0.84-1.27)

0.76

1.09

(0.79-1.49)

0.60

0.97

(0.75-1.26)

0.84

0.56

  1. ELSA-Brasil, 2008–2010.
  2. Through logistic regression, as follows:
  3. Model 1: age.
  4. Model 2: model 1 + sex, glycated hemoglobin, duration of diabetes, use of insulin.
  5. Excursion versus obesity interaction.