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Table 2 Patient characteristics at baseline by treatment continuity during 24 month follow-up (n = 1,110)

From: A real world comparison of sulfonylurea and insulin vs. incretin-based treatments in patients not controlled on prior metformin monotherapy

 

Met/Incr (n = 635)

Met/SU (n = 255)

Insulin ± any OAD (n = 220)

Stable

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Stable

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Stable

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(n = 421; 66.3%)

(n = 214; 33.7%)

(n = 154; 60.4%)

(n = 101; 39.6%)

(n = 151; 68.6%)

(n = 69; 31.4%)

Age (years)

65.6 (57.7–73.0)

61.6 (55.0–69.2)

68.6 (59.6–73.2)

64.8 (56.8–71.2)

64.0 (54.6–72.9)

58.8 (54.1–65.1)

Female gender (%)

48.7

48.6

51.9

34.7

42.4

44.9

Body weight (kg)

89 (78–101)

91 (80–104)

87 (77–95)

86 (79–103)

90 (80–106)

89 (78–98)

Diabetes duration (years)

4.6 (2.1–7.6)

4.5 (1.7–7.8)

5.3 (2.4–8.6)

5.0 (2.5–8.6)

7.1 (3.6–10.7)

5.6 (2.6–8.3)

Blood glucose

      

 HbA1c (%)

7.2 (6.8–7.7)

7.4 (6.8–8.0)

7.1 (6.7–7.9)

7.3 (6.9–8.2)

8.3 (7.3–9.6)

7.9 (7.1–8.9)

 FPG (mg/dl)

134 (116–158)

140 (120–165)

135 (114–158)

133 (117–158)

156 (130–206)

150 (123–182)

 PPG (mg/dl)

174 (146–210)

178 (145–210)

177 (158–207)

169 (154–196)

202 (171–239)

198 (165–235)

Anamnestic hypoglycaemia* (%)

2.9

5.1

4.5

7.9

19.2

43.5

Concomitant disease (%)

      

 MACCE (%)

9.3

10.3

11.7

10.0

12.0

4.3

 Macrovasc. complication (%)

12.9

16.0

14.3

14.0

20.0

8.7

 Microvasc. complication (%)

12.1

18.7

10.3

13.9

23.2

11.6

  1. Legend: Met/Incr, metformin/incretin; Met/SU, metformin/sulfonylurea; OAD, oral antidiabetic drug; HbA1c, glycosylated haemoglobin A1c, FPG, fasting plasma glucose; PPG, postprandial plasma glucose; MACCE, major cardiac or cerebrovascular event; *within 12 months prior to baseline.