Median changes in blood pressure and lipids, by end-point body weight change quartiles. (A) SBP. (B) DBP. (C) HDL-C. (D) LDL-C. (E) Total cholesterol. (F) Triglycerides. DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure. The central line represents the median (also labelled above the plot), the box encloses the 25th to 75th percentiles of the distribution, and the outer bars are drawn to the 10th and 90th percentiles.