Body weight and risk of atrial fibrillation in 7,169 patients with newly diagnosed type 2 diabetes; an observational study

Table 3 Relative risks of atrial fibrillation in hazard ratios according to weight change groups

	All	Weight gain		Stable weight		Weight loss
Total cohort
-number of patients	7169	1023		3736		2410
-number of AF events	287	49		139		99
Model A: Hazard ratio (95% CI)		1.54	(1.11–2.14)	1.00	Reference	1.07	(0.82–1.39)
Model B: Hazard ratio (95% CI)		1.53	(1.10–2.12)	1.00	Reference	1.06	(0.81–1.38)
Subgroup with BMI ≥ 30
-number of patients	3840	468		1790		1582
-number of AF events	170	27		78		65
Model A: Hazard ratio (95% CI)		1.60	(1.03–2.49)	1.00	Reference	0.94	(0.67–1.31)
Model B: Hazard ratio (95% CI)		1.59	(1.02–2.47)	1.00	Reference	0.93	(0.67–1.30)

Model A: Adjustments for age, gender, body mass index at baseline and previous angina pectoris. Model B: Adjustments as in Model A + systolic blood pressure; included imputation of missing blood pressure data. AF = atrial fibrillation, CI = confidence interval, BMI = body mass index.

ISSN: 1475-2840