|
All
|
Weight gain
|
Stable weight
|
Weight loss
|
---|
Total cohort
| | | | |
-number of patients
|
7169
|
1023
|
3736
|
2410
|
-number of AF events
|
287
|
49
|
139
|
99
|
Model A: Hazard ratio (95% CI)
| |
1.54
|
(1.11–2.14)
|
1.00
|
Reference
|
1.07
|
(0.82–1.39)
|
Model B: Hazard ratio (95% CI)
| |
1.53
|
(1.10–2.12)
|
1.00
|
Reference
|
1.06
|
(0.81–1.38)
|
Subgroup with BMI ≥ 30
| | | | |
-number of patients
|
3840
|
468
|
1790
|
1582
|
-number of AF events
|
170
|
27
|
78
|
65
|
Model A: Hazard ratio (95% CI)
| |
1.60
|
(1.03–2.49)
|
1.00
|
Reference
|
0.94
|
(0.67–1.31)
|
Model B: Hazard ratio (95% CI)
| |
1.59
|
(1.02–2.47)
|
1.00
|
Reference
|
0.93
|
(0.67–1.30)
|
- Model A: Adjustments for age, gender, body mass index at baseline and previous angina pectoris. Model B: Adjustments as in Model A + systolic blood pressure; included imputation of missing blood pressure data. AF = atrial fibrillation, CI = confidence interval, BMI = body mass index.