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Table 2 Diastolic dysfunction parameters according to quartiles of insulin resistance and metabolic syndrome status

From: Diastolic dysfunction in the diabetic continuum: association with insulin resistance, metabolic syndrome and type 2 diabetes

  Diastolic function parameters
  E’ velocity E/E’ ratio E/A ratio DT
Insulin resistance     
(HOMA-IR score)     
Quartile 1 11.3 ± 3.3 6.8 ± 2.6 1.03 ± 0.37 232.8 ± 52.8
Quartile 2 10.7 ± 2.9 7.1 ± 2.3 0.97 ± 0.28 233.2 ± 50.4
Quartile 3 10.1 ± 3.6 7.6 ± 2.7 0.92 ± 0.27 240.8 ± 69.5
Quartile 4 9.8 ± 3.0 8.1 ± 3.1 0.92 ± 0.35 245.5 ± 54.3
No Metabolic Syndrome (n = 571) 11.2 ± 3.3 6.9 ± 2.3 1.01 ± 0.32 232.3 ± 56.9
Metabolic Syndrome without T2DM ( n = 331) 9.7 ± 3.1 7.8 ± 2.7 0.88 ± 0.25 248.4 ± 57.2
Metabolic Syndrome with T2DM (n = 123) 9.2 ± 2.8 9.0 ± 3.6 0.95 ± 0.46 237.9 ± 52.7
 p for trend p < 0.001 p < 0.001 p < 0.001 p = 0.002
  1. DT - deceleration time; T2DM - type 2 diabetes mellitus; HOMA-IR - Homeostasis Model Assessment of Insulin Resistance.
  2. Results are presented as mean ± standard deviation.