TY - JOUR AU - Redfield, M. M. AU - Jacobsen, S. J. AU - Burnett, J. C. AU - Mahoney, D. W. AU - Bailey, K. R. AU - Rodeheffer, R. J. PY - 2003 DA - 2003// TI - Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic JO - JAMA VL - 289 UR - https://doi.org/10.1001/jama.289.2.194 DO - 10.1001/jama.289.2.194 ID - Redfield2003 ER - TY - JOUR AU - Kane, G. C. AU - Karon, B. L. AU - Mahoney, D. W. AU - Redfield, M. M. AU - Roger, V. L. AU - Burnett, J. C. PY - 2011 DA - 2011// TI - Progression of left ventricular diastolic dysfunction and risk of heart failure JO - JAMA VL - 306 UR - https://doi.org/10.1001/jama.2011.1201 DO - 10.1001/jama.2011.1201 ID - Kane2011 ER - TY - JOUR AU - Mogelvang, R. AU - Sogaard, P. AU - Pedersen, S. A. AU - Olsen, N. T. AU - Marott, J. L. AU - Schnohr, P. PY - 2009 DA - 2009// TI - Cardiac dysfunction assessed by echocardiographic tissue Doppler imaging is an independent predictor of mortality in the general population JO - Circulation VL - 119 UR - https://doi.org/10.1161/CIRCULATIONAHA.108.793471 DO - 10.1161/CIRCULATIONAHA.108.793471 ID - Mogelvang2009 ER - TY - STD TI - Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Jr., Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, et al.: 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2013. ID - ref4 ER - TY - JOUR AU - Russo, C. AU - Jin, Z. AU - Homma, S. AU - Rundek, T. AU - Elkind, M. S. AU - Sacco, R. L. PY - 2011 DA - 2011// TI - Effect of obesity and overweight on left ventricular diastolic function: a community-based study in an elderly cohort JO - J Am Coll Cardiol VL - 57 UR - https://doi.org/10.1016/j.jacc.2010.10.042 DO - 10.1016/j.jacc.2010.10.042 ID - Russo2011 ER - TY - JOUR AU - Canepa, M. AU - Strait, J. B. AU - Abramov, D. AU - Milaneschi, Y. AU - AlGhatrif, M. AU - Moni, M. PY - 2012 DA - 2012// TI - Contribution of central adiposity to left ventricular diastolic function (from the Baltimore Longitudinal Study of Aging) JO - Am J Cardiol VL - 109 UR - https://doi.org/10.1016/j.amjcard.2011.11.054 DO - 10.1016/j.amjcard.2011.11.054 ID - Canepa2012 ER - TY - JOUR AU - Canepa, M. AU - Strait, J. B. AU - Milaneschi, Y. AU - Alghatrif, M. AU - Ramachandran, R. AU - Makrogiannis, S. PY - 2013 DA - 2013// TI - The relationship between visceral adiposity and left ventricular diastolic function: Results from the Baltimore Longitudinal Study of Aging JO - Nutr Metab Cardiovasc Dis VL - 23 UR - https://doi.org/10.1016/j.numecd.2013.04.003 DO - 10.1016/j.numecd.2013.04.003 ID - Canepa2013 ER - TY - JOUR AU - Ingelsson, E. AU - Sundstrom, J. AU - Arnlov, J. AU - Zethelius, B. AU - Lind, L. PY - 2005 DA - 2005// TI - Insulin resistance and risk of congestive heart failure JO - JAMA VL - 294 UR - https://doi.org/10.1001/jama.294.3.334 DO - 10.1001/jama.294.3.334 ID - Ingelsson2005 ER - TY - JOUR AU - Horwich, T. B. AU - Fonarow, G. C. PY - 2010 DA - 2010// TI - Glucose, obesity, metabolic syndrome, and diabetes relevance to incidence of heart failure JO - J Am Coll Cardiol VL - 55 UR - https://doi.org/10.1016/j.jacc.2009.07.029 DO - 10.1016/j.jacc.2009.07.029 ID - Horwich2010 ER - TY - JOUR AU - Zabalgoitia, M. AU - Ismaeil, M. F. AU - Anderson, L. AU - Maklady, F. A. PY - 2001 DA - 2001// TI - Prevalence of diastolic dysfunction in normotensive, asymptomatic patients with well-controlled type 2 diabetes mellitus JO - Am J Cardiol VL - 87 UR - https://doi.org/10.1016/S0002-9149(00)01366-7 DO - 10.1016/S0002-9149(00)01366-7 ID - Zabalgoitia2001 ER - TY - JOUR AU - Boudina, S. AU - Abel, E. D. PY - 2007 DA - 2007// TI - Diabetic cardiomyopathy revisited JO - Circulation VL - 115 UR - https://doi.org/10.1161/CIRCULATIONAHA.106.679597 DO - 10.1161/CIRCULATIONAHA.106.679597 ID - Boudina2007 ER - TY - JOUR AU - Stahrenberg, R. AU - Edelmann, F. AU - Mende, M. AU - Kockskamper, A. AU - Dungen, H. D. AU - Scherer, M. PY - 2010 DA - 2010// TI - Association of glucose metabolism with diastolic function along the diabetic continuum JO - Diabetologia VL - 53 UR - https://doi.org/10.1007/s00125-010-1718-8 DO - 10.1007/s00125-010-1718-8 ID - Stahrenberg2010 ER - TY - JOUR AU - Bajraktari, G. AU - Koltai, M. S. AU - Ademaj, F. AU - Rexhepaj, N. AU - Qirko, S. AU - Ndrepepa, G. PY - 2006 DA - 2006// TI - Relationship between insulin resistance and left ventricular diastolic dysfunction in patients with impaired glucose tolerance and type 2 diabetes JO - Int J Cardiol VL - 110 UR - https://doi.org/10.1016/j.ijcard.2005.08.033 DO - 10.1016/j.ijcard.2005.08.033 ID - Bajraktari2006 ER - TY - JOUR AU - Mottillo, S. AU - Filion, K. B. AU - Genest, J. AU - Joseph, L. AU - Pilote, L. AU - Poirier, P. PY - 2010 DA - 2010// TI - The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis JO - J Am Coll Cardiol VL - 56 UR - https://doi.org/10.1016/j.jacc.2010.05.034 DO - 10.1016/j.jacc.2010.05.034 ID - Mottillo2010 ER - TY - JOUR AU - DelasFuentes, L. AU - Brown, A. L. AU - Mathews, S. J. AU - Waggoner, A. D. AU - Soto, P. F. AU - Gropler, R. J. PY - 2007 DA - 2007// TI - Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass JO - Eur Heart J VL - 28 ID - DelasFuentes2007 ER - TY - JOUR AU - Azevedo, A. AU - Bettencourt, P. AU - Almeida, P. B. AU - Santos, A. C. AU - Abreu-Lima, C. AU - Hense, H. W. PY - 2007 DA - 2007// TI - Increasing number of components of the metabolic syndrome and cardiac structural and functional abnormalities–cross-sectional study of the general population JO - BMC Cardiovasc Disord VL - 7 UR - https://doi.org/10.1186/1471-2261-7-17 DO - 10.1186/1471-2261-7-17 ID - Azevedo2007 ER - TY - JOUR AU - Seo, J. M. AU - Park, T. H. AU - Lee, D. Y. AU - Cho, Y. R. AU - Baek, H. K. AU - Park, J. S. PY - 2011 DA - 2011// TI - Subclinical Myocardial Dysfunction in Metabolic Syndrome Patients without Hypertension JO - J Cardiovasc Ultrasound VL - 19 UR - https://doi.org/10.4250/jcu.2011.19.3.134 DO - 10.4250/jcu.2011.19.3.134 ID - Seo2011 ER - TY - JOUR AU - Grundy, S. M. AU - Cleeman, J. I. AU - Daniels, S. R. AU - Donato, K. A. AU - Eckel, R. H. AU - Franklin, B. A. PY - 2005 DA - 2005// TI - Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement JO - Circulation VL - 112 UR - https://doi.org/10.1161/CIRCULATIONAHA.105.169404 DO - 10.1161/CIRCULATIONAHA.105.169404 ID - Grundy2005 ER - TY - JOUR AU - Cortez-Dias, N. AU - Martins, S. AU - Belo, A. AU - Fiuza, M. PY - 2011 DA - 2011// TI - Comparison of definitions of metabolic syndrome in relation to risk for coronary artery disease and stroke JO - Rev Port Cardiol VL - 30 ID - Cortez-Dias2011 ER - TY - JOUR AU - Matthews, D. R. AU - Hosker, J. P. AU - Rudenski, A. S. AU - Naylor, B. A. AU - Treacher, D. F. AU - Turner, R. C. PY - 1985 DA - 1985// TI - Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man JO - Diabetologia VL - 28 UR - https://doi.org/10.1007/BF00280883 DO - 10.1007/BF00280883 ID - Matthews1985 ER - TY - JOUR AU - Lang, R. M. AU - Bierig, M. AU - Devereux, R. B. AU - Flachskampf, F. A. AU - Foster, E. AU - Pellikka, P. A. PY - 2006 DA - 2006// TI - Recommendations for chamber quantification JO - Eur J Echocardiogr VL - 7 UR - https://doi.org/10.1016/j.euje.2005.12.014 DO - 10.1016/j.euje.2005.12.014 ID - Lang2006 ER - TY - JOUR AU - Nagueh, S. F. AU - Appleton, C. P. AU - Gillebert, T. C. AU - Marino, P. N. AU - Oh, J. K. AU - Smiseth, O. A. PY - 2009 DA - 2009// TI - Recommendations for the evaluation of left ventricular diastolic function by echocardiography JO - Eur J Echocardiogr VL - 10 UR - https://doi.org/10.1093/ejechocard/jep007 DO - 10.1093/ejechocard/jep007 ID - Nagueh2009 ER - TY - JOUR AU - Dinh, W. AU - Lankisch, M. AU - Nickl, W. AU - Scheyer, D. AU - Scheffold, T. AU - Kramer, F. PY - 2010 DA - 2010// TI - Insulin resistance and glycemic abnormalities are associated with deterioration of left ventricular diastolic function: a cross-sectional study JO - Cardiovasc Diabetol VL - 9 UR - https://doi.org/10.1186/1475-2840-9-63 DO - 10.1186/1475-2840-9-63 ID - Dinh2010 ER - TY - JOUR AU - Utsunomiya, H. AU - Yamamoto, H. AU - Kunita, E. AU - Hidaka, T. AU - Kihara, Y. PY - 2014 DA - 2014// TI - Insulin resistance and subclinical abnormalities of global and regional left ventricular function in patients with aortic valve sclerosis JO - Cardiovasc Diabetol VL - 13 UR - https://doi.org/10.1186/1475-2840-13-86 DO - 10.1186/1475-2840-13-86 ID - Utsunomiya2014 ER - TY - JOUR AU - Beltran-Sanchez, H. AU - Harhay, M. O. AU - Harhay, M. M. AU - McElligott, S. PY - 2013 DA - 2013// TI - Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999–2010 JO - J Am Coll Cardiol VL - 62 UR - https://doi.org/10.1016/j.jacc.2013.05.064 DO - 10.1016/j.jacc.2013.05.064 ID - Beltran-Sanchez2013 ER - TY - JOUR AU - Masugata, H. AU - Senda, S. AU - Goda, F. AU - Yoshihara, Y. AU - Yoshikawa, K. AU - Fujita, N. PY - 2006 DA - 2006// TI - Left ventricular diastolic dysfunction as assessed by echocardiography in metabolic syndrome JO - Hypertens Res VL - 29 UR - https://doi.org/10.1291/hypres.29.897 DO - 10.1291/hypres.29.897 ID - Masugata2006 ER - TY - JOUR AU - Ayalon, N. AU - Gopal, D. M. AU - Mooney, D. M. AU - Simonetti, J. S. AU - Grossman, J. R. AU - Dwivedi, A. PY - 2014 DA - 2014// TI - Preclinical Left Ventricular Diastolic Dysfunction in Metabolic Syndrome JO - Am J Cardiol VL - 114 UR - https://doi.org/10.1016/j.amjcard.2014.06.013 DO - 10.1016/j.amjcard.2014.06.013 ID - Ayalon2014 ER - TY - JOUR AU - Abel, E. D. AU - O'Shea, K. M. AU - Ramasamy, R. PY - 2012 DA - 2012// TI - Insulin resistance: metabolic mechanisms and consequences in the heart JO - Arterioscler Thromb Vasc Biol VL - 32 UR - https://doi.org/10.1161/ATVBAHA.111.241984 DO - 10.1161/ATVBAHA.111.241984 ID - Abel2012 ER - TY - JOUR AU - Peterson, L. R. AU - Herrero, P. AU - Schechtman, K. B. AU - Racette, S. B. AU - Waggoner, A. D. AU - Kisrieva-Ware, Z. PY - 2004 DA - 2004// TI - Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women JO - Circulation VL - 109 UR - https://doi.org/10.1161/01.CIR.0000127959.28627.F8 DO - 10.1161/01.CIR.0000127959.28627.F8 ID - Peterson2004 ER - TY - JOUR AU - Ogata, T. AU - Miyauchi, T. AU - Sakai, S. AU - Takanashi, M. AU - Irukayama-Tomobe, Y. AU - Yamaguchi, I. PY - 2004 DA - 2004// TI - Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway JO - J Am Coll Cardiol VL - 43 UR - https://doi.org/10.1016/j.jacc.2003.11.043 DO - 10.1016/j.jacc.2003.11.043 ID - Ogata2004 ER - TY - JOUR AU - Anderson, E. A. AU - Hoffman, R. P. AU - Balon, T. W. AU - Sinkey, C. A. AU - Mark, A. L. PY - 1991 DA - 1991// TI - Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans JO - J Clin Invest VL - 87 UR - https://doi.org/10.1172/JCI115260 DO - 10.1172/JCI115260 ID - Anderson1991 ER - TY - JOUR AU - Park, J. S. AU - Nam, J. S. AU - Cho, M. H. AU - Yoo, J. S. AU - Ahn, C. W. AU - Jee, S. H. PY - 2010 DA - 2010// TI - Insulin resistance independently influences arterial stiffness in normoglycemic normotensive postmenopausal women JO - Menopause VL - 17 ID - Park2010 ER - TY - JOUR AU - MacIsaac, R. J. AU - Thomas, M. C. AU - Panagiotopoulos, S. AU - Smith, T. J. AU - Hao, H. AU - Matthews, D. G. PY - 2008 DA - 2008// TI - Association between intrarenal arterial resistance and diastolic dysfunction in type 2 diabetes JO - Cardiovasc Diabetol VL - 7 UR - https://doi.org/10.1186/1475-2840-7-15 DO - 10.1186/1475-2840-7-15 ID - MacIsaac2008 ER - TY - JOUR AU - Ceriello, A. AU - Taboga, C. AU - Tonutti, L. AU - Quagliaro, L. AU - Piconi, L. AU - Bais, B. PY - 2002 DA - 2002// TI - Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment JO - Circulation VL - 106 UR - https://doi.org/10.1161/01.CIR.0000027569.76671.A8 DO - 10.1161/01.CIR.0000027569.76671.A8 ID - Ceriello2002 ER - TY - JOUR AU - Kuster, G. M. AU - Lancel, S. AU - Zhang, J. AU - Communal, C. AU - Trucillo, M. P. AU - Lim, C. C. PY - 2010 DA - 2010// TI - Redox-mediated reciprocal regulation of SERCA and Na + −Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes JO - Free Radic Biol Med VL - 48 UR - https://doi.org/10.1016/j.freeradbiomed.2010.01.038 DO - 10.1016/j.freeradbiomed.2010.01.038 ID - Kuster2010 ER - TY - JOUR AU - Fuseya, T. AU - Furuhashi, M. AU - Yuda, S. AU - Muranaka, A. AU - Kawamukai, M. AU - Mita, T. PY - 2014 DA - 2014// TI - Elevation of circulating fatty acid-binding protein 4 is independently associated with left ventricular diastolic dysfunction in a general population JO - Cardiovasc Diabetol VL - 13 UR - https://doi.org/10.1186/s12933-014-0126-7 DO - 10.1186/s12933-014-0126-7 ID - Fuseya2014 ER - TY - JOUR AU - Stratmann, B. AU - Tschoepe, D. PY - 2011 DA - 2011// TI - Heart in diabetes: not only a macrovascular disease JO - Diabetes Care VL - 34 UR - https://doi.org/10.2337/dc11-s208 DO - 10.2337/dc11-s208 ID - Stratmann2011 ER - TY - JOUR AU - Goldin, A. AU - Beckman, J. A. AU - Schmidt, A. M. AU - Creager, M. A. PY - 2006 DA - 2006// TI - Advanced glycation end products: sparking the development of diabetic vascular injury JO - Circulation VL - 114 UR - https://doi.org/10.1161/CIRCULATIONAHA.106.621854 DO - 10.1161/CIRCULATIONAHA.106.621854 ID - Goldin2006 ER - TY - JOUR AU - Lind, M. AU - Bounias, I. AU - Olsson, M. AU - Gudbjornsdottir, S. AU - Svensson, A. M. AU - Rosengren, A. PY - 2011 DA - 2011// TI - Glycaemic control and incidence of heart failure in 20,985 patients with type 1 diabetes: an observational study JO - Lancet VL - 378 UR - https://doi.org/10.1016/S0140-6736(11)60471-6 DO - 10.1016/S0140-6736(11)60471-6 ID - Lind2011 ER - TY - JOUR AU - Aurigemma, G. P. AU - Gottdiener, J. S. AU - Shemanski, L. AU - Gardin, J. AU - Kitzman, D. PY - 2001 DA - 2001// TI - Predictive value of systolic and diastolic function for incident congestive heart failure in the elderly: the cardiovascular health study JO - J Am Coll Cardiol VL - 37 UR - https://doi.org/10.1016/S0735-1097(01)01110-X DO - 10.1016/S0735-1097(01)01110-X ID - Aurigemma2001 ER - TY - JOUR AU - Bella, J. N. AU - Palmieri, V. AU - Roman, M. J. AU - Liu, J. E. AU - Welty, T. K. AU - Lee, E. T. PY - 2002 DA - 2002// TI - Mitral ratio of peak early to late diastolic filling velocity as a predictor of mortality in middle-aged and elderly adults: the Strong Heart Study JO - Circulation VL - 105 UR - https://doi.org/10.1161/01.CIR.0000015076.37047.D9 DO - 10.1161/01.CIR.0000015076.37047.D9 ID - Bella2002 ER - TY - JOUR AU - Holland, D. J. AU - Kumbhani, D. J. AU - Ahmed, S. H. AU - Marwick, T. H. PY - 2011 DA - 2011// TI - Effects of treatment on exercise tolerance, cardiac function, and mortality in heart failure with preserved ejection fraction. A meta-analysis JO - J Am Coll Cardiol VL - 57 UR - https://doi.org/10.1016/j.jacc.2010.10.057 DO - 10.1016/j.jacc.2010.10.057 ID - Holland2011 ER - TY - JOUR AU - Banerjee, D. AU - Biggs, M. L. AU - Mercer, L. AU - Mukamal, K. AU - Kaplan, R. AU - Barzilay, J. PY - 2013 DA - 2013// TI - Insulin resistance and risk of incident heart failure: Cardiovascular Health Study JO - Circ Heart Fail VL - 6 UR - https://doi.org/10.1161/CIRCHEARTFAILURE.112.000022 DO - 10.1161/CIRCHEARTFAILURE.112.000022 ID - Banerjee2013 ER - TY - JOUR AU - Vardeny, O. AU - Gupta, D. K. AU - Claggett, B. AU - Burke, S. AU - Shah, A. AU - Loehr, L. PY - 2013 DA - 2013// TI - Insulin resistance and incident heart failure the ARIC study (Atherosclerosis Risk in Communities) JO - JACC Heart Fail VL - 1 UR - https://doi.org/10.1016/j.jchf.2013.07.006 DO - 10.1016/j.jchf.2013.07.006 ID - Vardeny2013 ER - TY - JOUR AU - Bibbins-Domingo, K. AU - Lin, F. AU - Vittinghoff, E. AU - Barrett-Connor, E. AU - Hulley, S. B. AU - Grady, D. PY - 2004 DA - 2004// TI - Predictors of heart failure among women with coronary disease JO - Circulation VL - 110 UR - https://doi.org/10.1161/01.CIR.0000141726.01302.83 DO - 10.1161/01.CIR.0000141726.01302.83 ID - Bibbins-Domingo2004 ER - TY - JOUR AU - Burla, A. K. AU - Lobato, N. S. AU - Fortes, Z. B. AU - Oigman, W. AU - Neves, M. F. PY - 2013 DA - 2013// TI - Cardiac fibrosis and vascular remodeling are attenuated by metformin in obese rats JO - Int J Cardiol VL - 165 UR - https://doi.org/10.1016/j.ijcard.2011.09.012 DO - 10.1016/j.ijcard.2011.09.012 ID - Burla2013 ER - TY - JOUR AU - Cittadini, A. AU - Napoli, R. AU - Monti, M. G. AU - Rea, D. AU - Longobardi, S. AU - Netti, P. A. PY - 2012 DA - 2012// TI - Metformin prevents the development of chronic heart failure in the SHHF rat model JO - Diabetes VL - 61 UR - https://doi.org/10.2337/db11-1132 DO - 10.2337/db11-1132 ID - Cittadini2012 ER - TY - JOUR AU - Xiao, X. AU - He, Q. AU - Lu, C. AU - Werle, K. D. AU - Zhao, R. X. AU - Chen, J. PY - 2012 DA - 2012// TI - Metformin impairs the growth of liver kinase B1-intact cervical cancer cells JO - Gynecol Oncol VL - 127 UR - https://doi.org/10.1016/j.ygyno.2012.06.032 DO - 10.1016/j.ygyno.2012.06.032 ID - Xiao2012 ER - TY - JOUR AU - Zhang, C. X. AU - Pan, S. N. AU - Meng, R. S. AU - Peng, C. Q. AU - Xiong, Z. J. AU - Chen, B. L. PY - 2011 DA - 2011// TI - Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats JO - Clin Exp Pharmacol Physiol VL - 38 UR - https://doi.org/10.1111/j.1440-1681.2010.05461.x DO - 10.1111/j.1440-1681.2010.05461.x ID - Zhang2011 ER - TY - JOUR AU - Ladeiras-Lopes, R. AU - Fontes-Carvalho, R. AU - Bettencourt, N. AU - Sampaio, F. AU - Gama, V. AU - Leite-Moreira, A. F. PY - 2014 DA - 2014// TI - METformin in DIastolic Dysfunction of MEtabolic syndrome (MET-DIME) trial: rationale and study design: MET-DIME trial JO - Cardiovasc Drugs Ther VL - 28 UR - https://doi.org/10.1007/s10557-014-6512-2 DO - 10.1007/s10557-014-6512-2 ID - Ladeiras-Lopes2014 ER -