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Table 3 Values of cardiovascular risk factors, organ damage markers and vascular structure and function parameters according to CAVI value

From: Cardio-ankle vascular index is associated with cardiovascular target organ damage and vascular structure and function in patients with diabetes or metabolic syndrome, LOD-DIABETES study: a case series report

Value of CAVI

CAVI < 9 (58%) Mean/Median/SD/IQR

CAVI ≥ 9 (42%) Mean/Median/SD/IQR

p-value

Age (years)

56.5 ± 11.4

67.7 ± 7.3

<0.01

Waist circumference (cm)

102.9 ± 10.7

102.2 ± 12.6

0.77

Body mass index (kg/m2)

30.6 ± 4.2

29.2 ± 5.1

0.13

Total Cholesterol (mg/dL)

191.7 ± 28.1

176.6 ± 35.0

0.02

LDL cholesterol (mg/dL)

115.0 ± 28.3

102.2 ± 30.7

0.03

Tryglicerides (mg/dL)

128 (96.0-161.5)

113.5 (82.5-159.5)

0.57

HDL cholesterol (mg/dL)

50.6 ± 12.0

50.1 ± 11.5

0.85

Lipid lowering drugs n (%)

32 (52.5)

35 (79.5)

<0.01

Diabetics n (%)

32 (52.5)

35 (79.5)

<0.01

Serum glucose (mg/dL)

96 (85.5-120.5)

107 (93.0-130.8)

0.05

HbA1c

6.1 (5.6-6.5)

6.6 (5.9-7.1)

0.03

Antidiabetic drugs n (%)

31 (50.8)

31 (70.5)

0.05

Office SBP (mm Hg)

127 ± 14

139 ± 17

<0.01

Office DBP (mm Hg)

77 ± 9

78 ± 10

0.59

Antihypertensive Drugs n (%)

50 (82.0)

36 (81.8)

0.98

CVR Framingham D’Agostino

20.5 ± 17.1

32.0 ± 20.8

<0.01

Serum creatinine (mg/dL)

0.9 (0.8-1.0)

0.8 (0.7-1.0)

0.69

GFR with MDRD-IDMS (mL/min/1.73 m2)

92.3 ± 19.1

87.6 ± 20.0

0.22

Albumin/creatinine (mg/g)

2.97 (0.00-8.25)

2.31 (0.00-14.03)

0.93

Cornell VDP (mmms)

1548.5 ± 389.6

1661.5 ± 893.1

0.38

Sokolow (mm)

20.26 ± 5.91

19.72 ± 7.04

0.68

Ankle/brachial index

1.14 ± 0.11

1.14 ± 0.10

0.95

Carotid IMT average mean (mm)

0.74 ± 0.10

0.84 ± 0.13

<0.01

cf-PWV (m/sec)

8.63 ± 2.63

10.86 ± 2.05

<0.01

ba-PWV (m/sec)

13.18 ± 1.41

16.96 ± 3.44

<0.01

Central Augmentation Index

25.2 ± 14.8

30.0 ± 10.1

0.06

Peripheral augmentation index

90 (75–93)

92.5 (83–105)

0.04

Arteriole-venule ratio

0.73 ± 0.11

0.76 ± 0.12

0.29

  1. CAVI: Cardio-Ankle Vascular Index. LDL: Low Density Lipoprotein. HDL: High Density Lipoprotein. HbA1C: Glycosylated Hemoglobin. SBP: Systolic Blood Pressure. DBP: Diastolic Blood Pressure. CVR: CardioVascular Risk. GFR: Glomerular filtration rate. MDRD-IDMS: Modification of Diet in Renal Disease-Isotopic Dilution Mass Spectrometry. VDP: Voltage–Duration Product. IMT: Intima-Media Thickness. cf-PWV: carotid femoral Pulse Wave Velocity. ba-PWV: brachial ankle Pulse Wave Velocity.