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Table 5 DIABHYCAR cohort: Characteristics of participants at baseline by the incidence of myocardial infarction and all-cause mortality during follow-up

From: Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with type 1 and type 2 diabetes

  Myocardial infarction during follow-up All-cause mortality
No Yes p No Yes p
N 3042 95   2554 438  
Male sex (%) 73.0 75.8 0.54 72.2 77.2 0.03
Age (years) 65.6 ± 8.3 65.9 ± 8.8 0.79 64.8 ± 8.1 70.5 ± 8.5 <0.0001
Duration of diabetes (years) 10.4 ± 7.7 11.3 ± 8.6 0.49 10.1 ± 7.6 12.3 ± 8.2 <0.0001
Body mass index (kg/m2) 29.4 ± 4.6 29.1 ± 4.2 0.60 29.5 ± 4.6 28.8 ± 4.9 0.0008
Systolic blood pressure (mmHg) 144 ± 13 146 ± 16 0.14 144 ± 13 146 ± 13 0.007
Diastolic blood pressure (mmHg) 82 ± 8 81 ± 8 0.29 82 ± 8 82 ± 8 0.99
HbA1c (%) and (mmol/mol) 7.9 ± 1.8 (62 ± 19) 8.2 ± 1.8 (66 ± 20) 0.06 7.8 ± 1.7 (62 ± 19) 8.0 ± 2.0 (64 ± 22) 0.35
Urinary albumin excretion (mg/l) 76 (144) 78 (162) 0.92 72 (130) 109 (278) <0.0001
eGFR (ml/min) 78 ± 22 75 ± 20 0.14 78 ± 22 72 ± 21 <0.0001
Total cholesterol (mmol/l) 5.79 ± 1.07 6.00 ± 1.25 0.18 5.78 ± 1.05 5.84 ± 1.15 0.37
HDL- cholesterol (mmol/l) 1.32 ± 0.36 1.25 ± 0.26 0.15 1.32 ± 0.35 1.29 ± 0.34 0.17
LDL- cholesterol (mmol/l) 3.52 ± 0.88 3.72 ± 1.02 0.10 3.53 ± 0.87 3.51 ± 0.92 0.61
Triglycerides (mmol/l) 1.83 (1.36) 1.81 (1.77) 0.53 1.84 (1.32) 1.84 (1.49) 0.69
Lipids lowering therapy (%) 35.5 33.7 0.71 36.0 32.2 0.12
Antiplatelet drugs (%) 18.8 16.8 0.63 17.0 28.5 <0.0001
Tobacco smoking (%) 14.4 13.7 0.84 14.2 14.6 0.83
Arterial hypertension (%) 56.1 60.0 0.44 54.9 64.4 0.0002
Previous myocardial infarction (%) 5.3 10.5 0.03 4.9 8.5 0.003
  1. Results expressed as mean ± SD, except urinary albumin excretion (UAE) and triglycerides expressed as median and interquartile range. Statistics of quantitative parameters are ANOVA performed with log-transformed data, or Wilcoxon test (UAE, triglycerides). eGFR: estimated glomerular filtration rate. p < 0.05 is significant.