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Table 5 DIABHYCAR cohort: Characteristics of participants at baseline by the incidence of myocardial infarction and all-cause mortality during follow-up

From: Plasma extracellular superoxide dismutase concentration, allelic variations in the SOD3 gene and risk of myocardial infarction and all-cause mortality in people with type 1 and type 2 diabetes

 

Myocardial infarction during follow-up

All-cause mortality

No

Yes

p

No

Yes

p

N

3042

95

 

2554

438

 

Male sex (%)

73.0

75.8

0.54

72.2

77.2

0.03

Age (years)

65.6 ± 8.3

65.9 ± 8.8

0.79

64.8 ± 8.1

70.5 ± 8.5

<0.0001

Duration of diabetes (years)

10.4 ± 7.7

11.3 ± 8.6

0.49

10.1 ± 7.6

12.3 ± 8.2

<0.0001

Body mass index (kg/m2)

29.4 ± 4.6

29.1 ± 4.2

0.60

29.5 ± 4.6

28.8 ± 4.9

0.0008

Systolic blood pressure (mmHg)

144 ± 13

146 ± 16

0.14

144 ± 13

146 ± 13

0.007

Diastolic blood pressure (mmHg)

82 ± 8

81 ± 8

0.29

82 ± 8

82 ± 8

0.99

HbA1c (%) and (mmol/mol)

7.9 ± 1.8 (62 ± 19)

8.2 ± 1.8 (66 ± 20)

0.06

7.8 ± 1.7 (62 ± 19)

8.0 ± 2.0 (64 ± 22)

0.35

Urinary albumin excretion (mg/l)

76 (144)

78 (162)

0.92

72 (130)

109 (278)

<0.0001

eGFR (ml/min)

78 ± 22

75 ± 20

0.14

78 ± 22

72 ± 21

<0.0001

Total cholesterol (mmol/l)

5.79 ± 1.07

6.00 ± 1.25

0.18

5.78 ± 1.05

5.84 ± 1.15

0.37

HDL- cholesterol (mmol/l)

1.32 ± 0.36

1.25 ± 0.26

0.15

1.32 ± 0.35

1.29 ± 0.34

0.17

LDL- cholesterol (mmol/l)

3.52 ± 0.88

3.72 ± 1.02

0.10

3.53 ± 0.87

3.51 ± 0.92

0.61

Triglycerides (mmol/l)

1.83 (1.36)

1.81 (1.77)

0.53

1.84 (1.32)

1.84 (1.49)

0.69

Lipids lowering therapy (%)

35.5

33.7

0.71

36.0

32.2

0.12

Antiplatelet drugs (%)

18.8

16.8

0.63

17.0

28.5

<0.0001

Tobacco smoking (%)

14.4

13.7

0.84

14.2

14.6

0.83

Arterial hypertension (%)

56.1

60.0

0.44

54.9

64.4

0.0002

Previous myocardial infarction (%)

5.3

10.5

0.03

4.9

8.5

0.003

  1. Results expressed as mean ± SD, except urinary albumin excretion (UAE) and triglycerides expressed as median and interquartile range. Statistics of quantitative parameters are ANOVA performed with log-transformed data, or Wilcoxon test (UAE, triglycerides). eGFR: estimated glomerular filtration rate. p < 0.05 is significant.