Table 1 GENEDIAB/GENESIS pooled study: Characteristics of participants at baseline by the incidence of myocardial infarction and all-cause mortality during follow-up

N

735

49

712

72

Male sex (%)

53.8

69.4

0.03

53.7

70.8

0.005

Age (years)

42.6 ± 11.0

52.3 ± 12.5

<0.0001

42.7 ± 11.1

49.5 ± 12.6

<0.0001

Duration of diabetes (years)

27.1 ± 9.0

33.3 ± 11.6

0.0004

27.2 ± 9.1

31.3 ± 10.6

0.004

Body mass index (kg/m²)

24.2 ± 3.5

24.9 ± 3.7

0.24

24.4 ± 3.5

23.6 ± 3.8

0.07

Systolic blood pressure (mmHg)

134 ± 19

144 ± 21

0.0007

134 ± 19

142 ± 18

0.0005

Diastolic blood pressure (mmHg)

77 ± 11

80 ± 11

0.07

76 ± 11

80 ± 10

0.004

HbA1c (%) and (mmol/mol)

8.5 ± 1.5 (70 ± 16)

8.9 ± 1.5 (74 ± 16)

0.08

8.5 ± 1.4 (69 ± 15)

9.4 ± 2.3 (79 ± 25)

<0.0001

Urinary albumin excretion (mg/l)

21 (177)

43 (836)

0.22

19 (157)

188 (900)

<0.0001

eGFR (ml/min)

86 ± 47

70 ± 31

0.02

86 ± 46

69 ± 56

<0.0001

Total cholesterol* (mmol/l)

5.67 ± 1.51

5.91 ± 1.07

0.28

5.65 ± 1.42

5.76 ± 1.67

0.97

Lipids lowering therapy (%)

7.9

16.3

0.04

8.3

11.1

0.41

Tobacco smoking (%)

42.0

47.9

0.42

41.2

59.2

0.004

Arterial hypertension (%)

60.8

83.7

0.001

60.5

84.7

<0.0001

Previous myocardial infarction (%)

3.8

22.9

<0.0001

3.9

21.1

<0.0001