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Table 1 Baseline characteristics and haemodynamics

From: Increased haemodynamic adrenergic load with isoflurane anaesthesia in type 2 diabetic and obese rats in vivo

 

Non-Diabetic

Diabetic

Lean

Obese

Body weight (g)

333 ± 6

417 ± 14*

364 ± 7

584 ± 16*

Epididymal fat weight (g)

1.45 ± 0.16

6.38 ± 0.67*

2.77 ± 0.29

17.57 ± 1.04*

Epididymal fat/Tibia length (g.cm−1)

0.40 ± 0.06

1.92 ± 0.18*

0.65 ± 0.07

4.57 ± 0.31*

Heart weight (g)

1.49 ± 0.06

1.52 ± 0.06

1.37 ± 0.06

1.56 ± 0.08

Heart weight/Tibia length (g.cm−1)

0.41 ± 0.02

0.44 ± 0.02

0.32 ± 0.02

0.40 ± 0.02*

Fasting plasma glucose (mmol.L−1)

6.4 ± 0.4

19.5 ± 4.4*

6.6 ± 0.3

7.1 ± 0.8

Fasting plasma insulin (ng.mL−1)

1.2 ± 0.3

8.0 ± 2.2*

1.1 ± 0.4

12.8 ± 3.2*

Mean arterial pressure (mmHg)

   Conscious

110.2 ± 4.7

114.4 ± 3.5

106.2 ± 4.7

125.9 ± 5.5*

   Anaesthetised

87.5 ± 4.4†

90.8 ± 7.6†

86.1 ± 5.8†

111.2 ± 5.0*†

Heart rate (bpm)

   Conscious

366 ± 16

317 ± 11*

389 ± 10

391 ± 10

   Anaesthetised

314 ± 10†

292 ± 4†

365 ± 7†

365 ± 6†

  1. Baseline characteristics of 16 week old Zucker Diabetic Fatty (ZDF) and Zucker Obese rats and their lean littermates. *significantly different from control littermates, †significantly different anaesthetised vs. conscious, n = 6-9, p < 0.05, values are means ± SE.