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Table 2 Association between vascular calcified plaque quintiles and mortality in DHS participants based on Cox Proportional Hazards regression

From: Prediction of mortality using a multi-bed vascular calcification score in the Diabetes Heart Study

 

Model 1

Model 2

Model 3

All-cause mortality

 

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

CAC

1.57 (1.34-1.76)

5.22 × 10−10

1.45 (1.24-1.69)

2.42 × 10−6

1.39 (1.18-1.63)

6.55 × 10−5

CarCP

1.58 (1.40-1.78)

1.57 × 10−13

1.41 (1.24-1.60)

1.23 × 10−7

1.36 (1.20-1.55)

3.28 × 10−6

AACP

1.55 (1.36-1.77)

6.22 × 10−11

1.37 (1.20-1.56)

3.80 × 10−6

1.30 (1.14-1.49)

0.0001

Multi-bed

1.65 (1.44-1.90)

1.60 × 10−12

1.49 (1.28-1.72)

1.70 × 10−7

1.42 (1.22-1.66)

6.11 × 10−6

CVD mortality

CAC

1.60 (1.31-1.96)

3.86 × 10−6

1.47 (1.18-1.83)

0.0007

1.40 (1.12-1.75)

0.003

CarCP

1.72 (1.44-2.07)

5.92 × 10−9

1.49 (1.23-1.81)

4.83 × 10−5

1.46 (1.20-1.77)

0.0001

AACP

1.73 (1.39-2.16)

7.77 × 10−7

1.49 (1.18-1.88)

0.0009

1.44 (1.14-1.81)

0.002

Multi-bed

1.91 (1.52-2.39)

1.87 × 10−8

1.68 (1.33-2.12)

1.57 × 10−5

1.63 (1.29-2.07)

5.11 × 10−5

  1. Hazard Ratios (HR) and confidence intervals (CI) are for each incremental increase in calcified plaque quintiles.
  2. Model 1: unadjusted; Model 2: adjusted for age and sex; Model 3: adjusted for age, sex, total cholesterol, HDL-cholesterol, smoking, systolic blood pressure, and anti-hypertensive medication use.
  3. CAC: coronary artery calcified plaque; CarCP: carotid artery calcified plaque; AACP – abdominal aortic calcified plaque.