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Table 1 Effects of linagliptin on body weight and various organ weights in salt-loaded DS rats

From: DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

   High Na
Normal Na Veh Lin
Body weight (g) 378 ± 9 367 ± 5 353 ± 5
Lung weight/tibia length (mg/mm) 37 ± 1 39 ± 2 37 ± 1
Liver weight/tibia length (mg/mm) 320 ± 4# 344 ± 8 324 ± 6#
Kidney weight/tibia length (mg/mm) 70 ± 1* 95 ± 2 92 ± 1
  1. Normal Na, normal-salt diet-fed DS rats, Veh, vehicle-treated DS rats fed high-salt diet, Lin, linagliptin-treated DS rats fed high-salt diet. Values are the means ± SEM (n = 7-11). Statistical analysis was performed by one-factor analysis of variation (ANOVA) followed by post hoc Fisher’s protected least significant difference test. #P < 0.05,
  2. *P < 0.01 vs Veh.