| | |
High Na
|
|---|
|
Normal Na
|
Veh
|
Lin
|
|---|
|
Body weight (g)
|
378 ± 9
|
367 ± 5
|
353 ± 5
|
|
Lung weight/tibia length (mg/mm)
|
37 ± 1
|
39 ± 2
|
37 ± 1
|
|
Liver weight/tibia length (mg/mm)
|
320 ± 4#
|
344 ± 8
|
324 ± 6#
|
|
Kidney weight/tibia length (mg/mm)
|
70 ± 1*
|
95 ± 2
|
92 ± 1
|
- Normal Na, normal-salt diet-fed DS rats, Veh, vehicle-treated DS rats fed high-salt diet, Lin, linagliptin-treated DS rats fed high-salt diet. Values are the means ± SEM (n = 7-11). Statistical analysis was performed by one-factor analysis of variation (ANOVA) followed by post hoc Fisher’s protected least significant difference test. #P < 0.05,
- *P < 0.01 vs Veh.
