Neointima formation after vascular injury in control and linagliptin-treated mice. Endothelial denudation injuries were induced in the left femoral artery of control (n =19) and linagliptin-treated mice (n =20). (A) Tissues were evaluated by staining with Elastica van Gieson, to visualize the internal elastic lamina (magnification, ×200). (B) The area of intima, media and intima/media was calculated for each group. Data are mean ± SEM. *p <0.05 vs. control. (C) Sham control vessels were stained with Elastica van Gieson.