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Figure 1 | Cardiovascular Diabetology

Figure 1

From: Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice

Figure 1

Immunization with AGE-LDL using Alum as adjuvant reduced atherosclerotic lesion burden of diabetic apoE -/- and LDLR-/ mice. A and B, Representative photomicrographs showing oil red O stained en face preparations of aortas (n = 10 in each group). C. Percentage of plaque area of total aortic area of diabetic apoE-/- and LDLR-/- mice treated with Alum adjuvant (bar with stripes), Alum + AGE-LDL immunization (black bar), and PBS treated controls (white bar). Mean ±SD values are shown. *indicates p < 0.05 vs. control, **indicates p < 0.01 vs. control, #indicates p < 0.05 vs. Alum adjuvant.

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Cardiovascular Diabetology

ISSN: 1475-2840