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Figure 8 | Cardiovascular Diabetology

Figure 8

From: Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice

Figure 8

Effect of long-term empagliflozin treatment on vascular relaxation by acetylcholine (A) and by SNAP (B), and vascular superoxide (C) in thoracic aortas of db/db mice. Upper panels in (C) are representative photomicrographs of dihydroethidium-stained aortic section. Bar = 50 μm. Abbreviations used are the same as in Figure 5. *p < 0.05, *p < 0.01, vs control db/db mice. Values are mean ± SEM (n = 9-11).

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