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Figure 10 | Cardiovascular Diabetology

Figure 10

From: Glycemic control with empagliflozin, a novel selective SGLT2 inhibitor, ameliorates cardiovascular injury and cognitive dysfunction in obese and type 2 diabetic mice

Figure 10

Effect of empagliflozin treatment on cerebral superoxide ((A)-(C)), cerebral 8-hydroxy-deoxyguanosine (8-OHdG) (D), gp91phox (E), p67phox (F), and brain-derived neurotrophic factor (BDNF)(G) of db/db mice. Upper panels in (A), (B), and (C) indicate representative photomicrograph of DHE-stained cerebral sections (hippocampus, cortex, and white matter, respectively). Upper panels in (E), (F), and (G) indicate representative Western blot band. Abbreviations used are the same as in Figure 1. Values are mean ± SEM (n = 11). *p < 0.05, *p < 0.01, vs control db/db mice.

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Cardiovascular Diabetology

ISSN: 1475-2840