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Table 3 Association of impaired fasting glucose, diabetes and their treatment with requirement for peripheral artery intervention in 1637 peripheral artery disease patients across 4 regression models

From: Association of impaired fasting glucose, diabetes and their management with the presentation and outcome of peripheral artery disease: a cohort study

  Model 1 Model 2 Model 3 Model 4
Patient group HR P value HR P value HR P value HR P value
(95% CI) (95% CI) (95% CI) (95% CI)
No diabetes 1.00   1.00   1.00   1.00  
(reference)   (reference)   (reference)   (reference)
Impaired fasting glucose 1.14 0.099 1.13 0.138 1.11 0.195 1.13 0.141
(0.98-1.33) (0.96-1.32) (0.95-1.30) (0.96-1.32)
Non-medicated diabetes 1.33 0.011 1.31 0.016 1.29 0.026 1.31 0.020
(1.07-1.66) (1.05-1.64) (1.03-1.61) (1.04-1.64)
Diabetes prescribed oral hypoglycaemics only 0.98 0.790 0.96 0.682 0.93 0.434 0.94 0.496
(0.81-1.17) (0.80-1.16) (0.77-1.12) (0.77-1.13)
Diabetes prescribed insulin 0.90 0.542 0.79 0.179 0.82 0.260 0.83 0.299
(0.65-1.25) (0.57-1.11) (0.58-1.16) (0.59-1.18)
  1. Models include the following covariates.
  2. Model 1: Age and sex.
  3. Model 2: Age, sex, hypertension, ever smoking, coronary heart disease and presenting complaint.
  4. Model 3: Age, sex, hypertension, ever smoking, coronary heart disease, presenting complaint, statin prescription, aspirin prescription, other anti-platelet prescription, beta blocker prescription, calcium channel blocker prescription, angiotensin converting enzyme inhibitor prescription, angiotensin receptor blocker prescription and frusemide prescription.
  5. Model 4: Age, sex, hypertension, ever smoking, coronary heart disease, presenting complaint, statin prescription, aspirin prescription, other anti-platelet prescription, beta blocker prescription, calcium channel blocker prescription, angiotensin converting enzyme inhibitor prescription, angiotensin receptor blocker prescription, frusemide prescription and eGFR. 15 patients with missing serum creatinine values were excluded from this analysis.