Association of impaired fasting glucose, diabetes and their management with the presentation and outcome of peripheral artery disease: a cohort study

Table 3 Association of impaired fasting glucose, diabetes and their treatment with requirement for peripheral artery intervention in 1637 peripheral artery disease patients across 4 regression models

	Model 1		Model 2		Model 3		Model 4
Patient group	HR	P value	HR	P value	HR	P value	HR	P value
Patient group	(95% CI)	P value	(95% CI)	P value	(95% CI)	P value	(95% CI)	P value
No diabetes	1.00		1.00		1.00		1.00
No diabetes	(reference)		(reference)		(reference)		(reference)
Impaired fasting glucose	1.14	0.099	1.13	0.138	1.11	0.195	1.13	0.141
Impaired fasting glucose	(0.98-1.33)	0.099	(0.96-1.32)	0.138	(0.95-1.30)	0.195	(0.96-1.32)	0.141
Non-medicated diabetes	1.33	0.011	1.31	0.016	1.29	0.026	1.31	0.020
Non-medicated diabetes	(1.07-1.66)	0.011	(1.05-1.64)	0.016	(1.03-1.61)	0.026	(1.04-1.64)	0.020
Diabetes prescribed oral hypoglycaemics only	0.98	0.790	0.96	0.682	0.93	0.434	0.94	0.496
Diabetes prescribed oral hypoglycaemics only	(0.81-1.17)	0.790	(0.80-1.16)	0.682	(0.77-1.12)	0.434	(0.77-1.13)	0.496
Diabetes prescribed insulin	0.90	0.542	0.79	0.179	0.82	0.260	0.83	0.299
Diabetes prescribed insulin	(0.65-1.25)	0.542	(0.57-1.11)	0.179	(0.58-1.16)	0.260	(0.59-1.18)	0.299

Models include the following covariates.
Model 1: Age and sex.
Model 2: Age, sex, hypertension, ever smoking, coronary heart disease and presenting complaint.
Model 3: Age, sex, hypertension, ever smoking, coronary heart disease, presenting complaint, statin prescription, aspirin prescription, other anti-platelet prescription, beta blocker prescription, calcium channel blocker prescription, angiotensin converting enzyme inhibitor prescription, angiotensin receptor blocker prescription and frusemide prescription.
Model 4: Age, sex, hypertension, ever smoking, coronary heart disease, presenting complaint, statin prescription, aspirin prescription, other anti-platelet prescription, beta blocker prescription, calcium channel blocker prescription, angiotensin converting enzyme inhibitor prescription, angiotensin receptor blocker prescription, frusemide prescription and eGFR. 15 patients with missing serum creatinine values were excluded from this analysis.

ISSN: 1475-2840