Cardiovascular Diabetology

Table 2 Correlation of endothelial biomarkers and characteristics of the study population

From: Biomarkers of endothelial dysfunction in relation to impaired carbohydrate metabolism following pregnancy with gestational diabetes mellitus

		sICAM-1			sVCAM-1			sE-selectin
	n	r	p-value	n	r	p-value	n	r	p-value
age	140	0.05	n.s.	140	0.04	n.s.	136	0.09	n.s.
BMI	136	0.25	0.004	136	0.21	0.016	132	0.35	<0.001
RRS	131	0.14	n.s.	131	0.10	n.s.	128	0.12	n.s.
RRD	131	0.11	n.s.	131	0.18	0.036	128	0.13	n.s.
SI (FSIGT)*	133	-0.23	0.009	133	-0.22	0.011	129	-0.21	0.018
OGIS (OGTT)*	137	-0.18	0.033	137	-0.23	0.007	133	-0.12	n.s.
ΔAIRg (FSIGT)*	133	-0.09	n.s.	133	0.04	n.s.	129	-0.04	n.s.
IGI (OGTT)*	139	-0.12	n.s.	139	0.03	n.s.	135	-0.10	n.s.
Total-Cholesterol	140	-0.03	n.s.	140	0.10	n.s.	136	-0.02	n.s.
LDL-Cholesterol	137	0.08	n.s.	137	0.13	n.s.	133	0.02	n.s.
HDL-Cholesterol	140	-0.30	0.001	140	0.06	n.s.	136	-0.16	n.s.
ln(Triglycerides)	140	0.12	n.s.	140	-0.02	n.s.	136	0.12	n.s.
ln(usCRP)	116	0.28	0.003	116	0.18	n.s.	114	0.04	n.s.
ln(IL-6)	93	0.13	n.s.	93	0.16	n.s.	94	0.24	0.019
ln(PAI-1)	132	0.29	<0.001	132	0.08	n.s.	128	0.21	0.016
Fibrinogen	140	0.25	0.003	140	0.04	n.s.	136	0.25	0.003

Data are number of observarion (n) and correlation coefficients (r). BMI (body mass index), RRS (systolic blood pressure), RRD (diastolic blood pressure), SI (insulin sensitivity index derived from the FSIGT), OGIS (oral glucose tolerance index derived from the OGTT), ΔAIRG (acute insulin response to glucose derived from the FSIGT), IGI (insulinogenic index), HDL (high density lipiprotein), LDL (low density lipoprotein), usCRP (ultrasensitive C-reactive protein), IL-6 (interleukin-6), PAI-1 (plasminogen activator inhibitor 1).
*Spearman’s rank correlation as used instead of Pearson’s product moment correlation due to nonlinear monotonic associations or outliers.

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ISSN: 1475-2840

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