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Table 1 Baseline characteristics categorized by insulin sensitivity status

From: Biomarkers of endothelial dysfunction in relation to impaired carbohydrate metabolism following pregnancy with gestational diabetes mellitus

 

n

Controls

n

pGDM-IS

n

pGDM-IR

p-value

Age (years)

40

31.2 ± 5.7

63

32.8 ± 4.2

39

32.9 ± 5.7

0.203

BMI (kg/m2)

37

25.2 ± 5.6

63

25.0  ± 3.5

39

30.5 ± 5.6

<0.001

OGIS, ml min-1 m-2

39

490.1  ± 71.0

63

463.6 ± 68.6

39

395.3 ± 72.7

<0.001

SI, 10-4 min-1 (μU/ml)-1

38

5.4  ± 2.6

63

5.3 ± 2.3

39

1.7  ± 0.6

<0.001

ΔAIRg (μu/ml)

38

54.4  ± 42.8

63

36.0  ± 22.7

39

50.3  ± 38.6

0.017

sICAM-1 (ng/ml)

39

238.0  ± 54.1

61

295.3  ± 70.5

35

304.1 ± 92.2

<0.001*

sVCAM-1 (ng/ml)

39

502.3 ± 164

61

600.3  ± 220

35

647.7  ± 159

0.001*

sE-selectin (ng/ml)

34

45.1  ± 18.5

61

48.6  ± 22.4

36

57.4  ± 27.4

0.026*

  1. Data are means ± standard deviation. BMI (body mass index), OGIS (oral glucose insulin sensitivityindex), SI (insulin sensitivity index),ΔAIRg (acute insulin response), sICAM-1 (soluble intracellular adhesion molecule-1), sVCAM-1 (soluble vascular cell adhesion molecule-1), sE-selectin (soluble E-selectin).
  2. *p-values are based on a test of linear trend.