| Oral | Glargine | NPH Insulin | all | p |
---|---|---|---|---|---|
N | 13 | 20 | 22 | 55 | Â |
Age (yrs) | 64.1 +/-4.1 | 60.1 +/-7.3 | 61.5 +/-5.0 | 61.6 +/-5.9 | 0.168 |
Gender (female/male;%) | 6 (46)/7 (54) | 7 (35)/13 (65) | 9 (41)/13 (59) | 22 (40)/33 (60) | 0.810 |
BMI (kg/m 2 ) | 30.1 +/-5.4 | 32.7 +/-6.0 | 31.8 +/-5.2 | 31.7 +/-5.5 | 0.417 |
Diabetes duration (yrs) | 6.2 +/-4.0 | 8.7 +/-6.6 | 9.8 +/-7.2 | 8.5 +/-6.4 | 0.286 |
Diabetic neuropathy (yes: n;%) | 3 (23) | 7 (37) | 7 (35) | 17 (33) | 0.690 |
Diabetic nephropathy (yes: n;%) | 0 | 3 (16) | 2 (10) | 5 (9) | 0.324 |
Diabetic retinopathy (yes: n;%) | 1 (8) | 2 (10) | 2 (10) | 5 (9) | 0.974 |
Systolic blood pressure (mmHg) | 142.5 +/-14.3 | 145.1 +/-14.8 | 141.2 +/-12.9 | 142.9 +/-13.8 | 0.666 |
Diastolic blood pressure (mmHg) | 79.6 +/-11.6 | 80.0 +/-10.2 | 79.1 +/-8.1 | 79.5 +/-9.6 | 0.964 |
HbA1c (%) | 7.3 +/-0.7 | 7.3 +/-0.9 | 7.5 +/-0.7 | 7.4 +/-0.8 | 0.713 |
Fasting Glucose (mg/dl) | 150.7 +/-41.1 | 166.8 +/-50.1 | 165.9 +/-38.9 | 162.6 +/-43.5 | 0.534 |
Serum Creatinin (mg/dl) | 0.8 +/-0.2 | 0.9 +/-0.2 | 0.8 +/-0.2 | 0.8 +/-0.2 | 0.451 |
Triglycerides (mg/dl) | 206.4 +/-131.2 | 208.9 +/-168.7 | 215.2 +/-110.7 | 210.8 +/-136.5 | 0.981 |
HDL-cholesterol (mg/dl) | 48.5 +/-18.2 | 44.2 +/-10.0 | 44.2 +/-12.8 | 45.2 +/-13.3 | 0.599 |
LDL-cholesterol (mg/dl) | 97.9 +/-30.0 | 88.1 +/-39.6 | 99.0 +/-27.5 | 94.8 +/-32.6 | 0.559 |
Hemoglobin (g/dl) | 14.2 +/-1.0 | 13.6 +/-1.4 | 14.1 +/-1.3 | 13.9 +/-1.3 | 0.363 |
Leukocyte count /nl | 6.3 +/-1.3 | 7.1 +/-2.2 | 7.5 +/-1.8 | 7.1 +/-1.9 | 0.187 |
Statins (yes: n;%) | 7 (54) | 14 (70) | 10 (45) | 31 (56) | 0.271 |
Intima media thickness (mm) | 0.83 +/-0.13 | 0.79 +/-0.13 | 0.79 +/-0.17 | 0.80 +/-0.14 | 0.737 |
Skin microvascular function (%) | 555.1 +/-223.5 | 408.4 +/-216.5 | 455.7 +/-171.8 | 462.0 +/-205.5 | 0.132 |