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Table 1 Baseline patient characteristics (visit 1)

From: Influence of insulin and glargine on outgrowth and number of circulating endothelial progenitor cells in type 2 diabetes patients: a partially double-blind, randomized, three-arm unicenter study

 

Oral

Glargine

NPH Insulin

all

p

N

13

20

22

55

 

Age (yrs)

64.1 +/-4.1

60.1 +/-7.3

61.5 +/-5.0

61.6 +/-5.9

0.168

Gender (female/male;%)

6 (46)/7 (54)

7 (35)/13 (65)

9 (41)/13 (59)

22 (40)/33 (60)

0.810

BMI (kg/m 2 )

30.1 +/-5.4

32.7 +/-6.0

31.8 +/-5.2

31.7 +/-5.5

0.417

Diabetes duration (yrs)

6.2 +/-4.0

8.7 +/-6.6

9.8 +/-7.2

8.5 +/-6.4

0.286

Diabetic neuropathy (yes: n;%)

3 (23)

7 (37)

7 (35)

17 (33)

0.690

Diabetic nephropathy (yes: n;%)

0

3 (16)

2 (10)

5 (9)

0.324

Diabetic retinopathy (yes: n;%)

1 (8)

2 (10)

2 (10)

5 (9)

0.974

Systolic blood pressure (mmHg)

142.5 +/-14.3

145.1 +/-14.8

141.2 +/-12.9

142.9 +/-13.8

0.666

Diastolic blood pressure (mmHg)

79.6 +/-11.6

80.0 +/-10.2

79.1 +/-8.1

79.5 +/-9.6

0.964

HbA1c (%)

7.3 +/-0.7

7.3 +/-0.9

7.5 +/-0.7

7.4 +/-0.8

0.713

Fasting Glucose (mg/dl)

150.7 +/-41.1

166.8 +/-50.1

165.9 +/-38.9

162.6 +/-43.5

0.534

Serum Creatinin (mg/dl)

0.8 +/-0.2

0.9 +/-0.2

0.8 +/-0.2

0.8 +/-0.2

0.451

Triglycerides (mg/dl)

206.4 +/-131.2

208.9 +/-168.7

215.2 +/-110.7

210.8 +/-136.5

0.981

HDL-cholesterol (mg/dl)

48.5 +/-18.2

44.2 +/-10.0

44.2 +/-12.8

45.2 +/-13.3

0.599

LDL-cholesterol (mg/dl)

97.9 +/-30.0

88.1 +/-39.6

99.0 +/-27.5

94.8 +/-32.6

0.559

Hemoglobin (g/dl)

14.2 +/-1.0

13.6 +/-1.4

14.1 +/-1.3

13.9 +/-1.3

0.363

Leukocyte count /nl

6.3 +/-1.3

7.1 +/-2.2

7.5 +/-1.8

7.1 +/-1.9

0.187

Statins (yes: n;%)

7 (54)

14 (70)

10 (45)

31 (56)

0.271

Intima media thickness (mm)

0.83 +/-0.13

0.79 +/-0.13

0.79 +/-0.17

0.80 +/-0.14

0.737

Skin microvascular function (%)

555.1 +/-223.5

408.4 +/-216.5

455.7 +/-171.8

462.0 +/-205.5

0.132