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Table 1 Clinical and biochemical parameters, angiographic findings and echocardiographic estimation of left ventricular ejection fraction in CAD and non-CAD

From: Serum levels of retinol-binding protein-4 are associated with the presence and severity of coronary artery disease

 

CAD group (n = 305)

Non-CAD group (n = 91)

P value

Males, n (%)

269 (88.20)

74 (81.32)

0.229

Age (y)

64 ± 13

62 ± 11

0.563

Smoking, n (%)

149 (48.85)

23 (25.27)

<0.001

Hypertension, n (%)

195 (63.93)

61 (67.03)

0.109

Dyslipidemia, n (%)

253 (82.95)

61 (67.03)

0.049

Diabetes, n (%)

74 (24.26)

16 (17.58)

0.184

Medications

   

Statins, n (%)

159 (52.13)

25 (27.47)

<0.001

Fibrates, n (%)

6 (1.97)

2 (2.2)

0.902

ACEIs/ARBs, n (%)

152 (49.83)

48 (52.75)

0.891

Anti-platelets, n (%)

178 (58.36)

15 (16.48)

<0.001

BMI (kg/m 2 )

28.93 ± 4.60

27.71 ± 4.22

0.088

WHR

0.97 ± 0.11

0.95 ± 0.09

0.133

SBP (mmHg)

145 ± 23

130 ± 17

<0.001

DBP (mmHg)

81 ± 13

80 ± 12

0.310

TChol (mg/dl)

193 ± 46

201 ± 52

0.401

HDL-C (mg/dl)

44 ± 13

48 ± 13

<0.001

LDL-C (mg/dl)

121 ± 43

128 ± 43

0.398

TG (mg/dl)

142 ± 77

132 ± 66

0.280

FPG (mg/dl)

135 ± 67

120 ± 25

0.045

HbA1c (%)*

7.7 ± 1.1

7.1 ± .9

0.020

Insulin (mU/L)

15.03 ± 8.71

9.01 ± 4.73

0.004

HOMA-IR

5.01 ± 2.45

2.67 ± 0.72

0.001

WBC (cells/μL)

9489 ± 3384

6826 ± 1858

<0.001

hsCRP (mg/L)

9.24 ± 3.16

2.97 ± 1.28

<0.001

RBP-4 (mg/L)

39.29 ± 11.72

24.83 ± 11.27

<0.001

LVEF (%)

54 ± 9

58 ± 9

0.009

Angiography

   

1-vessel

126 (41.31)

-

-

2-vessels

131 (42.95)

-

-

3-/4-vessels

48 (15.74)

-

-

  1. Data are expressed as means ± SD. n, number of patients; ACEIs, Angiotensin-converting enzyme inhibitors; ARBs, Angiotensin II Receptor Blockers; BMI, body-mass index; WHR, waist-hip ratio; SBP, systolic blood pressure, DBP, diastolic blood pressure; TChol, total cholesterol; TG, triglycerides; FPG, fasting plasma glucose; HOMA-IR, homeostasis model assessment; WBC, white blood cells; hsCRP, high-sensitivity CRP; LVEF, left ventricular ejection fraction.
  2. *HbA1c was measured only in the diabetic subgroup.