| BW | MAP | LVSP | LVEDP | LV + dP/dT | LV -dP/dT | Plasma glucose |
---|
(g) | (mmHg) | (mmHg) | (mmHg) | (mmHg/sec) | (mmHg/sec) |
---|
Sham (N = 5) | 312 ± 1 | 117 ± 3 | 148 ± 8 | 8 ± 1 | 6963 ± 188 | 6069 ± 172 | 10 ± 2 |
STZ (N = 5) | 263 ± 2* | 87 ± 1* | 109 ± 1* | 10 ± 1 | 5656 ± 79* | 4155 ± 53* | 29 ± 1* |
- STZ indicates streptozotocin-induced diabetic rats, BW, body weight, MAP, mean arterial pressure, LVSP, left ventricular systolic pressure, LVEDP, left ventricular end-diastolic pressure, +dp/dt, rate of contraction; -dp/dt rate of relaxation, LV, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.