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Table 2 Cardiac function of normal and streptozotocin-induced type I diabetic rats

From: Nestin downregulation in rat vascular smooth muscle cells represents an early marker of vascular disease in experimental type I diabetes

 

BW

MAP

LVSP

LVEDP

LV + dP/dT

LV -dP/dT

Plasma glucose

(g)

(mmHg)

(mmHg)

(mmHg)

(mmHg/sec)

(mmHg/sec)

Sham (N = 5)

312 ± 1

117 ± 3

148 ± 8

8 ± 1

6963 ± 188

6069 ± 172

10 ± 2

STZ (N = 5)

263 ± 2*

87 ± 1*

109 ± 1*

10 ± 1

5656 ± 79*

4155 ± 53*

29 ± 1*

  1. STZ indicates streptozotocin-induced diabetic rats, BW, body weight, MAP, mean arterial pressure, LVSP, left ventricular systolic pressure, LVEDP, left ventricular end-diastolic pressure, +dp/dt, rate of contraction; -dp/dt rate of relaxation, LV, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.