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Table 2 Cardiac function of normal and streptozotocin-induced type I diabetic rats

From: Nestin downregulation in rat vascular smooth muscle cells represents an early marker of vascular disease in experimental type I diabetes

  BW MAP LVSP LVEDP LV + dP/dT LV -dP/dT Plasma glucose
(g) (mmHg) (mmHg) (mmHg) (mmHg/sec) (mmHg/sec)
Sham (N = 5) 312 ± 1 117 ± 3 148 ± 8 8 ± 1 6963 ± 188 6069 ± 172 10 ± 2
STZ (N = 5) 263 ± 2* 87 ± 1* 109 ± 1* 10 ± 1 5656 ± 79* 4155 ± 53* 29 ± 1*
  1. STZ indicates streptozotocin-induced diabetic rats, BW, body weight, MAP, mean arterial pressure, LVSP, left ventricular systolic pressure, LVEDP, left ventricular end-diastolic pressure, +dp/dt, rate of contraction; -dp/dt rate of relaxation, LV, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.