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Table 1 Vascular remodeling of the carotid artery and aorta of normal and streptozotocin-induced type I diabetic rats

From: Nestin downregulation in rat vascular smooth muscle cells represents an early marker of vascular disease in experimental type I diabetes

 

Aortic arch

Carotid artery

Sham (N = 6)

STZ (N = 6)

Sham (N = 4-5)

STZ (N = 4-5)

Total density (cells/mm2)

3114 ± 204

2693 ± 284

2869 ± 223

2710 ± 237

PHH3(+) (cells/mm2)

1032 ± 201

137 ± 28*

797 ± 124

416 ± 108*

PHH3(+)/Nestin(-) (cells/mm2)

645 ± 131

84 ± 18*

430 ± 73

273 ± 87*

Nestin(+) (cells/mm2)

641 ± 89

385 ± 48*

590 ± 72

355 ± 64*

PHH3(+)/Nestin(+) (cells/mm2)

387 ± 77

52 ± 15*

368 ± 62

143 ± 36*

  1. STZ indicates streptozotocin-induced diabetic rats, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.
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Cardiovascular Diabetology

ISSN: 1475-2840