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Table 1 Vascular remodeling of the carotid artery and aorta of normal and streptozotocin-induced type I diabetic rats

From: Nestin downregulation in rat vascular smooth muscle cells represents an early marker of vascular disease in experimental type I diabetes

  Aortic arch Carotid artery
Sham (N = 6) STZ (N = 6) Sham (N = 4-5) STZ (N = 4-5)
Total density (cells/mm2) 3114 ± 204 2693 ± 284 2869 ± 223 2710 ± 237
PHH3(+) (cells/mm2) 1032 ± 201 137 ± 28* 797 ± 124 416 ± 108*
PHH3(+)/Nestin(-) (cells/mm2) 645 ± 131 84 ± 18* 430 ± 73 273 ± 87*
Nestin(+) (cells/mm2) 641 ± 89 385 ± 48* 590 ± 72 355 ± 64*
PHH3(+)/Nestin(+) (cells/mm2) 387 ± 77 52 ± 15* 368 ± 62 143 ± 36*
  1. STZ indicates streptozotocin-induced diabetic rats, data are presented as mean ± SEM, analyzed by unpaired t-test, (*) represents P < 0.05 versus sham and (N) number of rats examined.