Table 1 Effects of age on baseline body mass index and metabolic parameters
Young | Old | |||||
|---|---|---|---|---|---|---|
Control | Old-Control | Old + GLP-1 | ||||
n = 8 | n = 9 | p value* | n = 7 | p value* | p value ** | |
Age (years) | 3.5 ± 1 | 11.2 ± 1 | <0.01 | 11.9 ± 1 | <0.01 | NS |
BMI (kg/w2) | 25 ± 0.6 | 26 ± 0.7 | NS | 27 ± 1 | NS | NS |
Body Weight (kg) | 15 ± 3 | 15 ± 3 | NS | 16 ± 2 | NS | NS |
Glucose (mmol/L) | 5.2 ± 0.2 | 5.0 ± 0.2 | NS | 4.9 ± 0.3 | NS | NS |
NEFA (μmol/L) | 363 ± 52 | 897 ± 67 | <0.01 | 913 ± 75 | <0.01 | NS |
Insulin (pmol/L) | 33 ± 9 | 110 ± 13 | <0.01 | 99 ± 20 | <0.01 | NS |
Glucagon (pq/ml) | 26 ± 2 | 32 ± 9 | NS | 38 ± 8 | NS | NS |
Adiponectin (μg/ml) | 2.9 ± 0.6 | 2.7 ± 0.9 | NS | 2.9 ± 0.5 | NS | NS |
NE (pmol/ml) | 56 ± 13 | 396 ± 52 | <0.01 | 422 ± 40 | <0.01 | NS |