Table 1 Cardiac function and blood pressure parameters

WT (n=6)

91 ± 3

60 ± 4

2.7 ± 0.3

1.1 ± 0.1

27.8 ± 7.2

2.5 ± 0.5

619 ± 98

132 ± 4

81 ± 3

102 ± 22

EphA2-R-M (n=9)

82 ± 4

49 ± 4^*

2.7 ± 0.2

1.4 ± 0.2

27 ± 5.7

4.8 ± 1.5

636 ± 71

129 ± 4

77 ± 2

71 ± 15

WT STZ (n=8)

88 ± 2

57 ± 3

2.8 ± 0.2

1.2 ± 0.1

30.1 ± 4.7

3.6 ± 0.9

578 ± 98

185 ± 6*

107 ± 11*

69 ± 11

EphA2-R-M STZ (n=18)

78 ± 6

46 ± 6^●

2.7 ± 0.2

1.5 ± 0.2

27.8 ± 5.6

6.1 ± 2.4

492 ± 142^†

148 ± 4

91 ± 3

60 ± 15

WT 4d (n=7)

77 ± 1

45 ± 5

3.4 ± 0.4*

1.9 ± 0.3

51.0 ± 14.1*

13.5 ± 5.4*

658 ± 91

129 ± 8

73 ± 5

169 ± 51

EphA2-R-M 4d (n-8)

79 ± 3

46 ± 3

3.2 ± 0.1

1.7 ± 0.1

39.5 ± 2.2

8.5 ± 1.5

632 ± 93

126 ± 4

76 ± 3

94 ± 24^‡

WT STZ + 4d (n=7)

55 ± 13^‡

28 ± 8^‡

3.3 ± 0.3

2.4 ± 0.5^‡

44.9 ± 10.0

21.0 ± 9.1^‡

602 ± 98

127 ± 6

73 ± 7

107 ± 32^‡

EphA2-R-M STZ + 4d (n=11)

62 ± 12^¥

33 ± 8^¥

3.1 ± 0.7

2.1 ± 0.5

39.7 ± 18.6

15.4 ± 9.2

536 ± 80

130 ± 5

69 ± 2

81 ± 40