| | |
All patients
|
Q I
|
Q II
|
Q III
|
Q IV
|
Q V
|
P
|
|---|
|
n
| |
585
|
117
|
117
|
117
|
117
|
117
| |
|
HbA
1c
|
%
|
7.53 (1.53)
|
7.32 (1.36)
|
7.41 (1.52)
|
7.48 (1.46)
|
7.60 (1.55)
|
7.85 (1.72)
|
NS
|
|
HbA
1c
< 7.0%
|
%
|
43
|
49
|
47
|
45
|
40
|
35
|
0.0155
|
|
cholesterol (C)
|
mg.dl-1
|
175 (41)
|
179 (35)
|
180 (37)
|
168 (40)
|
174 (41)
|
174 (48)
|
NS
|
|
LDL-C
|
mg.dl-1
|
98 (35)
|
100 (32)
|
107 (34)
|
96 (34)
|
97 (34)
|
90 (38)
|
0.0047
|
|
non-HDL-C
|
mg.dl-1
|
131 (40)
|
118 (33)
|
132 (36)
|
127 (38)
|
136 (40)
|
143 (47)
|
<0.0001
|
|
non-HDL-C - LDL-C
|
mg.dl-1
|
31 (18)
|
18 (8)
|
25 (11)
|
30 (15)
|
38 (18)
|
47 (21)
|
<0.0001
|
|
HDL-C
|
mg.dl-1
|
44 (13)
|
61 (11)
|
48 (8)
|
42 (7)
|
38 (6)
|
32 (8)
|
~
|
|
apoA1
|
mg.dl-1
|
143 (27)
|
167 (23)
|
151 (24)
|
139 (20)
|
137 (18)
|
122 (26)
|
<0.0001
|
|
apoB
100
|
mg.dl-1
|
90 (26)
|
80 (23)
|
92 (26)
|
86 (24)
|
94 (25)
|
95 (30)
|
<0.0001
|
|
pre-LLD TG
|
mg.dl-1
|
204 (155)
|
102 (46)
|
149 (61)
|
173 (82)
|
217 (72)
|
359 (254)
|
~
|
|
current TG
|
mg.dl-1
|
171 (119)
|
92 (40)
|
129 (66)
|
153 (77)
|
200 (102)
|
282 (165)
|
~
|
|
LDL-C. apoB
100
-1
| |
1.07 (0.28)
|
1.21 (0.24)
|
1.13 (0.26)
|
1.07 (0.26)
|
0.99 (0.28)
|
0.92 (0.27)
|
<0.0001
|
|
hs
CRP
|
mg.dl-1
|
0.36 (0.61)
|
0.36 (0.73)
|
0.20 (0.21)
|
0.42 (0.72)
|
0.35 (0.44)
|
0.48 (0.76)
|
0.0089
|
|
uric acid
|
mg.dl-1
|
5.7 (1.6)
|
5.5 (1.4)
|
5.7 (1.5)
|
5.6 (1.7)
|
6.3 (1.6)
|
5.7 (1.6)
|
0.001
|
|
cystatin C
|
mg.l-1
|
0.87 (0.34)
|
0.76 (0.21)
|
0.85 (0.22)
|
0.85 (0.27)
|
0.90 (0.38)
|
0.98 (0.48)
|
<0.0001
|
|
white blood cells
|
103.mm-3
|
7.20 (1.94)
|
6.63 (2.04)
|
6.70 (1.90)
|
7.49 (1.90)
|
7.57 (2.01)
|
7.56 (1.58)
|
<0.0001
|
|
ALT
|
IU.l-1
|
32 (21)
|
27 (11)
|
33 (26)
|
30 (16)
|
38 (28)
|
32 (14)
|
0.0009
|
|
SHBG
|
nmol.l-1
|
37 (24)
|
46 (25)
|
37 (21)
|
31 (15)
|
36 (25)
|
34 (30)
|
<0.0001
|
|
eGFR
|
ml.min-1.1.73 m2
|
80 (27)
|
85 (25)
|
80 (23)
|
82 (29)
|
81 (24)
|
73 (30)
|
0.0105
|
|
albuminuria
|
μg.mg creatinine-1
|
100 (278)
|
50 (103)
|
30 (55)
|
108 (273)
|
106 (304)
|
201 (433)
|
<0.0001
|
|
normal/(μ)albuminuria
|
%
|
65/35
|
76/24
|
73/27
|
64/36
|
63/37
|
51/49
|
<0.0001
|
- Results are expressed as means (1 SD) or proportions (%). ALT: alanine aminotransferase; apo: apolipoprotein; eGFR: estimated glomerular filtration rate; HDL: high-density lipoprotein; hsCRP: high-sensitivity C-reactive protein; LDL: low-density lipoprotein; LLD: lipid-lowering drug(s); μ: micro-; Q: quintile; SHBG: sex hormone-binding globulin; TG: triglycerides. NS: not significant.
