| Metabolic syndrome | HOMA-IR | ||||||
---|---|---|---|---|---|---|---|---|
 | Men, N = 822 |  | Women, N = 1,097 |  | Men, N = 822 | Women, N = 1,097 | ||
 |  |  |  |  |  |  | Pearson's correlation | |
Characteristics | No N = 681 | Yes N = 141 | P-value* | No N = 927 | Yes N = 170 | P-value* | r (P-value) | r (P-value) |
Age (years) | 61 ± 14 | 60 ± 12 | 0.342 | 62 ± 12 | 66 ± 9 | 0.001 | -0.141 (<0.001) | 0.100 (0.001) |
Body mass index (kg/m2) | 23.1 ± 2.8 | 26.1 ± 2.6 | <0.001 | 22.8 ± 2.9 | 26.8 ± 3.6 | <0.001 | 0.547 (<0.001) | 0.516 (<0.001) |
Smoking status, % | 41.4/23.9/15.7/18.9 | 42.6/29.1/9.2/19.1 | 0.199 | 97.4/0.8/1.7/0.1 | 98.2/1.2/0.6/0 | 0.636 | -0.081 (0.020) | 0.019 (0.536) |
Alcohol consumption, % | 14.4/28.0/35.4/22.2 | 15.6/30.5/29.1/24.8 | 0.555 | 63.3/30.9/5.4/0.4 | 71.8/25.3/2.4/0.6 | 0.120 | -0.064 (0.066) | -0.049 (0.104) |
History of cardiovascular disease, % | 23.6 | 29.8 | 0.078 | 6.3 | 10.0 | 0.058 | 0.048 (0.171) | 0.051 (0.090) |
Systolic blood pressure (mmHg) | 139 ± 20 | 156 ± 17 | 0.001 | 136 ± 23 | 150 ± 20 | <0.001 | 0.137 (<0.001) | 0.245 (<0.001) |
Diastolic blood pressure (mmHg) | 84 ± 11 | 88 ± 10 | <0.001 | 79 ± 12 | 86 ± 10 | <0.001 | 0.181 (<0.001) | 0.230 (<0.001) |
Antihypertensive medication, % | 23.6 | 29.8 | 0.078 | 21.1 | 50.0 | <0.001 | 0.124 (<0.001) | 0.195 (<0.001) |
Triglycerides (mmol/L) | 1.00 (0.77-1.33) | 1.89 (1.52-2.60) | <0.001 | 0.94 (0.72-1.23) | 1.76 (1.21-2.12) | <0.001 | 0.392 (<0.001) | 0.365 (<0.001) |
HDL cholesterol (mmol/L) | 1.58 ± 0.37 | 1.27 ± 0.36 | <0.001 | 1.74 ± 0.38 | 1.32 ± 0.32 | <0.001 | -0.319 (<0.001) | -0.232 (<0.001) |
LDL cholesterol (mmol/L) | 2.83 ± 0.79 | 3.01 ± 0.92 | 0.019 | 3.24 ± 0.74 | 3.40 ± 0.85 | 0.011 | 0.206 (<0.001) | 0.200 (<0.001) |
Antilipidemic medication, % | 3.7 | 5.0 | 0.301 | 5.7 | 11.8 | 0.005 | 0.070 (0.044) | 0.088 (0.004) |
Serum uric acid (μmol/L) | 349 ± 81 | 360 ± 91 | 0.146 | 261 ± 61 | 291 ± 58 | <0.001 | 0.171 (<0.001) | 0.252 (<0.001) |
eGFR (mL/min/1.73 m2) | 80.9 ± 16.7 | 82.3 ± 18.6 | 0.385 | 80.9 ± 17.1 | 76.3 ± 16.2 | 0.001 | -0.009 (0.791) | -0.068 (0.024) |
Fasting blood glucose (mmol/L) | 5.22 (4.94-5.61) | 6.11 (5.27-6.83) | <0.001 | 5.05 (4.83-5.44) | 5.61 (5.11-6.61) | <0.001 | 0.474 (<0.001) | 0.540 (<0.001) |
HOMA-IR | 1.01 (0.65-1.64) | 2.21 (1.43-3.20) | <0.001 | 1.27 (0.85-1.79) | 2.52 (1.80-3.79) | <0.001 | ---------- | ---------- |
Diabetic medication, % | 2.8 | 9.9 | <0.001 | 2.2 | 8.8 | <0.001 | 0.112 (0.001) | 0.133 (<0.001) |
HMW adiponectin (μg/mL) | 3.63 (2.18-5.65) | 2.28 (1.60-3.69) | <0.001 | 7.09 (4.69-10.3) | 4.48 (3.12-7.17) | <0.001 | -0.331 (<0.001) | -0.340 (<0.001) |
hsCRP (mg/L) | 0.480 (0.275-1.015) | 0.690 (0.400-1.535) | <0.001 | 0.380 (0.200-0.760) | 0.750 (0.390-1.613) | <0.001 | 0.163 (<0.001) | 0.290 (<0.001) |
GGT (IU/L) | 35 (24-61) | 55 (36-102) | <0.001 | 20 (15-26) | 25 (19-35) | <0.001 | 0.240 (<0.001) | 0.328 (<0.001) |