New and known type 2 diabetes as coronary heart disease equivalent: results from 7.6 year follow up in a middle east population

Table 3 Hazard ratio of CHD event in men according to baseline DM and prior CHD status

	CHD event NO. (rate)^a	Age adjusted HR	p-value	Multivariate^b adjusted HR	p-value
DM-/CHD-	98 (7.8)	Ref		Ref
DM-/CHD+	46 (30.5)	2.8(1.9-4.0)	< 0.001	2.1(1.4-3.1)	< 0.001
NDM+/CHD-	26 (25.5)	2.4(1.5-3.7)	< 0.001	1.7(1.1-2.7)*	0.020
NDM+/CHD+	19 (63.3)	5.3(3.2-8.9)	< 0.001	3.2(1.9-5.6)	< 0.001
KDM+/CHD-	11 (24.7)	2.2(1.1-4.1)	0.017	1.7(0.9-3.3)†	0.108
KDM+/CHD+	12 (55.5)	4.7(2.5-8.7)	< 0.001	4.2(2.2-7.8)	< 0.001

^a Incidence rate: number of cases per 1000 person-year.
^b Analyses were adjusted for age, systolic blood pressure, body mass index, cholesterol, triglyceride/HDL-cholesterol, family history of cardiovascular disease, smoking and intervention.
* The p-value to compare with the HR of DM-/CHD+ was 0.414, applying Wald test.
† The p-value to compare with the HR of DM-/CHD+ was 0.527, applying Wald test.
DM: diabetes mellitus, CHD: coronary heart disease, NDM: newly diagnosed DM, KDM: known DM, HR: hazard ratio.

ISSN: 1475-2840