Table 2 Changes in Blood Gas, Hemoglobin, Respiratory Rate in STZ and Control rats during Normovolemic Hemodilution

Hb

(g/dL)

STZ

13.4 ± 1.2#

12.1 ± 0.2

11.6 ± 0.4

10.2 ± 1.2*

9.2 ± 0.1*

9.2 ± 0.5*

8.4 ± 0.1

Control

13.6 ± 1.2

12.8 ± 0.5

11.8 ± 1.2

10.2 ± 0.3*

9.5 ± 1.2*

9.0 ± 0.8*

8.2 ± 0.4*

pH

STZ

7.36 ± 0.03#

7.35 ± 0.03

7.37 ± 0.03

7.37 ± 0.01

7.37 ± 0.03

7.35 ± 0.02

7.35 ± 0.01

Control

7.44 ± 0.02

7.44 ± 0.03

7.43 ± 0.03

7.42 ± 0.01

7.43 ± 0.01

7.42 ± 0.01

7.39 ± 0.02*

P_aCO₂

(mmHg)

STZ

37.4 ± 5.4#

37.0 ± 4.1

33.7 ± 5.0

30.5 ± 3.3*

28.4 ± 2.1*

30.0 ± 2.1*

26.6 ± 2.5*

Control

41.4 ± 3.4

35.9 ± 2.1

30.8 ± 2.4*

31.5 ± 2.7*

29.1 ± 0.9*

27.0 ± 1.8*

25.9 ± 2.8*

HCO₃^-

(mmol/L)

STZ

22.5 ± 1.8#

21.7 ± 0.5

19.8 ± 1.3

18.3 ± 1.2*

18.0 ± 0.8*

16.6 ± 0.8*

13.6 ± 3.0*

Control

21.1 ± 1.6

19.81 ± 1.8

19.3 ± 1.0

19.4 ± 1.5

20.0 ± 0.7

19.6 ± 1.7

19.9 ± +1.3

BE'

(mEq/L)

STZ

-4.1 ± 1.0#

-4.3 ± 0.8

-4.5 ± 1.5

-4.6 ± 1.2

-4.8 ± 1.8

-6.0 ± 1.5*

-6.9 ± 1.2*

Control

0.8 ± 0.4

-0.8 ± 2.5

-2.3 ± 2.0*

-2.2 ± 2.0*

-2.4. ± 1.7*

-2.3 ± 2.6*

-1.3 ± 2.4*

RR

(times/nin)

STZ

85 ± 2

107 ± 15*

118 ± 16*

129 ± 10*

143 ± 14*

140 ± 6*

142 ± 11*

Control

83 ± 5

88 ± 6

111 ± 8*

118 ± 7*

110 ± 11*

108 ± 11*

116 ± 19*